Methimazole - Revision history

Danbot: Switch SMW query from broadtable to table format for better layout with TOC

2026-03-20T21:58:31Z

Switch SMW query from broadtable to table format for better layout with TOC

← Revisión anterior		Revisión del 21:58 20 mar 2026
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	\|?Has Route=Route		\|?Has Route=Route
	\|?Has Population=Population		\|?Has Population=Population
	\|format=~~broadtable~~		\|format=table
	\|headers=plain		\|headers=plain
	\|mainlabel=-		\|mainlabel=-

Danbot: Fix SMW query: replace link=subject with mainlabel=- to fix broken subobject fragment links

2026-03-20T17:26:13Z

Fix SMW query: replace link=subject with mainlabel=- to fix broken subobject fragment links

← Revisión anterior		Revisión del 17:26 20 mar 2026
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	\|format=broadtable		\|format=broadtable
	\|headers=plain		\|headers=plain
	\|~~link~~=~~subject~~		\|mainlabel=-
	\|sort=Has Indication		\|sort=Has Indication
	\|limit=50		\|limit=50

Danbot: Add dynamic SMW Indications by Condition table (auto-populated from disease pages via MedicationDose template)

2026-03-20T16:44:23Z

Add dynamic SMW Indications by Condition table (auto-populated from disease pages via MedicationDose template)

← Revisión anterior		Revisión del 16:44 20 mar 2026
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	==Comments==		==Comments==


			==Indications by Condition==
			''The following table is automatically generated from disease/condition pages across WikEM.''

			{{#ask:[[Has DrugName::Methimazole]]
			\|?Has Indication=Indication
			\|?Has Dose=Dose
			\|?Has Context=Context
			\|?Has Route=Route
			\|?Has Population=Population
			\|format=broadtable
			\|headers=plain
			\|link=subject
			\|sort=Has Indication
			\|limit=50
			}}

	==See Also==		==See Also==

ClaireLewis: /* References */

2019-09-22T23:15:12Z

References

← Revisión anterior		Revisión del 23:15 22 sep 2019
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	<references/>		<references/>
	[[Category:Pharmacology]]		[[Category:Pharmacology]]
			[[Category:Endocrinology]]

Bmurray990: /* Administration */

2019-01-26T21:33:46Z

Administration

← Revisión anterior		Revisión del 21:33 26 ene 2019
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	==Administration==		==Administration==
	*Type: Antithyroid		*Type: Antithyroid
	*Dosage Forms:		*Dosage Forms: Tablet; 5mg, 10mg
	*Routes of Administration: Oral		*Routes of Administration: Oral
	*Common Trade Names: Tapazole		*Common Trade Names: Tapazole

Mholtz: Text replacement - "OR" to "'''OR'''"

2017-05-31T00:23:13Z

Text replacement - "OR" to "'''OR'''"

← Revisión anterior		Revisión del 00:23 31 may 2017
Línea 16:		Línea 16:
	==Pediatric Dosing==		==Pediatric Dosing==
	*Hyperthyroidism:		*Hyperthyroidism:
	**Initial: 0.2-0.5 mg/kg PO daily OR 0.4mg/kg PO daily in 3 divided doses		**Initial: 0.2-0.5 mg/kg PO daily '''OR''' 0.4mg/kg PO daily in 3 divided doses
	**Maintenance: 50% of initial dose		**Maintenance: 50% of initial dose

ClaireLewis: /* Adult Dosing */

2016-11-14T01:08:23Z

Adult Dosing

← Revisión anterior		Revisión del 01:08 14 nov 2016
Línea 6:		Línea 6:

	==Adult Dosing==		==Adult Dosing==
	*Thyroid storm: 60 to 80 mg PO daily		*[[Thyroid storm]]: 60 to 80 mg PO daily
	*Amiodorone-induced thyrotoxicosis: 40mg PO daily until patient is euthyroid (usually 3-6mo)		*Amiodorone-induced thyrotoxicosis: 40mg PO daily until patient is euthyroid (usually 3-6mo)
	*Iodine-induced thyrotoxicosis: 20-40mg PO once		*Iodine-induced thyrotoxicosis: 20-40mg PO once
	*Hyperthyroidism		*[[Hyperthyroidism]]
	**Initial: 10-20mg/day (mild), 30-40mg/day (moderate), 60mg/day (severe) in 1-3 doses		**Initial: 10-20mg/day (mild), 30-40mg/day (moderate), 60mg/day (severe) in 1-3 doses
	**Maintenance: 5-15mg/day		**Maintenance: 5-15mg/day
	**2nd-3rd trimester pregnancy: Use lowest dose needed to keep maternal total T3/T4 ~~slighly~~ above normal range for pregnancy, TSH suppressed, and free T4 at or slightly above upper limit of normal for nonpregnant women		**2nd-3rd trimester pregnancy: Use lowest dose needed to keep maternal total T3/T4 slightly above normal range for pregnancy, TSH suppressed, and free T4 at or slightly above upper limit of normal for nonpregnant women

	==Pediatric Dosing==		==Pediatric Dosing==

ClaireLewis: Created page with "==Administration== Type: Antithyroid Dosage Forms: Routes of Administration: Oral Common Trade Names: Tapazole ==Adult Dosing== Thyroid storm: 60 to 80 mg PO daily Amio..."

2016-11-14T01:03:28Z

Created page with "==Administration== *Type: Antithyroid *Dosage Forms: *Routes of Administration: Oral *Common Trade Names: Tapazole ==Adult Dosing== *Thyroid storm: 60 to 80 mg PO daily *Amio..."

Página nueva

==Administration==
*Type: Antithyroid
*Dosage Forms:
*Routes of Administration: Oral
*Common Trade Names: Tapazole

==Adult Dosing==
*Thyroid storm: 60 to 80 mg PO daily
*Amiodorone-induced thyrotoxicosis: 40mg PO daily until patient is euthyroid (usually 3-6mo)
*Iodine-induced thyrotoxicosis: 20-40mg PO once
*Hyperthyroidism
**Initial: 10-20mg/day (mild), 30-40mg/day (moderate), 60mg/day (severe) in 1-3 doses
**Maintenance: 5-15mg/day
**2nd-3rd trimester pregnancy: Use lowest dose needed to keep maternal total T3/T4 slighly above normal range for pregnancy, TSH suppressed, and free T4 at or slightly above upper limit of normal for nonpregnant women

==Pediatric Dosing==
*Hyperthyroidism:
**Initial: 0.2-0.5 mg/kg PO daily OR 0.4mg/kg PO daily in 3 divided doses
**Maintenance: 50% of initial dose

==Special Populations==
*[[Drug Ratings in Pregnancy|Pregnancy Rating]]: D - see pregnancy dosing
*[[Lactation risk categories|Lactation risk]]: Infant risk cannot be ruled out
*Renal dosing: no adjustment
*Hepatic dosing: no adjustment

==Contraindications==
*Allergy to class/drug

==Adverse Reactions==
===Serious===
*Agranulocytosis, aplastic anemia
*Vasculitis
*Pancreatitis
*Hepatotoxicity
===Common===
*Rash

==Pharmacology==
*Half-life: 2-28h
*Metabolism: Hepatic
*Excretion: Renal

==Mechanism of Action==
*Inhibits thyroperoxidase, thus blocking synthesis of thyroid hormones

==Comments==

==See Also==
*[[Hyperthyroid]], [[Thyroid storm]]
*[[Propylthiouracil]]

==References==
<references/>
[[Category:Pharmacology]]