Kanamycin - Revision history

Danbot: Add See Also section

2026-03-22T09:12:08Z

Add See Also section

← Revisión anterior		Revisión del 09:12 22 mar 2026
Línea 58:		Línea 58:
	==Mechanism of Action==		==Mechanism of Action==
	*Interferes with protein synthesis in bacterial cell by binding to ribosomal subunit		*Interferes with protein synthesis in bacterial cell by binding to ribosomal subunit

			==See Also==
			*[[Aminoglycosides]]
			*[[Antibiotics]]
			*[[Tuberculosis]]

	==References==		==References==
	[[Category:Pharmacology]]		[[Category:Pharmacology]]
	[[Category:ID]]		[[Category:ID]]

Ostermayer at 15:09, 18 July 2025

2025-07-18T15:09:03Z

← Revisión anterior		Revisión del 15:09 18 jul 2025
Línea 1:		Línea 1:
	==Administration==		==Administration==
	*Type: [[Aminoglycoside]]		*Type: [[Is DrugClass::Aminoglycoside]]
	*Dosage Forms: 1 g/3 mL		*Dosage Forms: 1 g/3 mL
	*Routes of Administration: IM, IV		*Routes of Administration: IM, IV
Línea 60:		Línea 60:

	==References==		==References==
	~~<UpToDate, MicroMedex/>~~
	[[Category:Pharmacology]]		[[Category:Pharmacology]]
	[[Category:ID]]		[[Category:ID]]

ClaireLewis: /* References */

2019-09-22T22:17:01Z

References

← Revisión anterior		Revisión del 22:17 22 sep 2019
Línea 62:		Línea 62:
	<UpToDate, MicroMedex/>		<UpToDate, MicroMedex/>
	[[Category:Pharmacology]]		[[Category:Pharmacology]]
			[[Category:ID]]

Rossdonaldson1: /* Adverse Reactions */

2016-10-02T14:50:34Z

Adverse Reactions

← Revisión anterior		Revisión del 14:50 2 oct 2016
Línea 32:		Línea 32:

	==Adverse Reactions==		==Adverse Reactions==
			*Nephrotoxicity
			**Increased risk with renal impairment, high dose, prolonged treatment
			**Monitor renal function, peak/trough levels
			*Neuromuscular Blockade
			**Risk of respiratory paralysis possible with any route of administration

	===Black Box Warnings===		===Black Box Warnings===
	*Neurotoxicity/Ototoxicity		*Neurotoxicity/Ototoxicity
	**Increased risk with renal impairment, high dose, prolonged treatment		**Increased risk with renal impairment, high dose, prolonged treatment

	===Serious===		===Serious===
	*Nephrotoxicity		*Nephrotoxicity
	*Ototoxicity (auditory or vestibular)		*Ototoxicity (auditory or vestibular)
	*Neurotoxicity, neuromuscular blockade		*Neurotoxicity, neuromuscular blockade

	===Common===		===Common===
	*Hearing loss, tinnitus, vertigo		*Hearing loss, tinnitus, vertigo

Rossdonaldson1: /* Administration */

2016-10-02T14:49:44Z

Administration

← Revisión anterior		Revisión del 14:49 2 oct 2016
Línea 1:		Línea 1:
	==Administration==		==Administration==
	*Type: Aminoglycoside		*Type: [[Aminoglycoside]]
	*Dosage Forms: 1 g/3 mL		*Dosage Forms: 1 g/3 mL
	*Routes of Administration: IM, IV		*Routes of Administration: IM, IV

	*Nephrotoxicity
	**Increased risk with renal impairment, high dose, prolonged treatment
	**Monitor renal function, peak/trough levels

	*Neuromuscular Blockade
	**Risk of respiratory paralysis possible with any route of administration

	==Adult Dosing==		==Adult Dosing==

ClaireLewis at 21:49, 28 September 2016

2016-09-28T21:49:16Z

← Revisión anterior		Revisión del 21:49 28 sep 2016
Línea 3:		Línea 3:
	*Dosage Forms: 1 g/3 mL		*Dosage Forms: 1 g/3 mL
	*Routes of Administration: IM, IV		*Routes of Administration: IM, IV

	~~==Black Box Warnings==~~
	*Neurotoxicity/Ototoxicity
	**Increased risk with renal impairment, high dose, prolonged treatment

	*Nephrotoxicity		*Nephrotoxicity
Línea 34:		Línea 30:
	*Allergy to class/drug		*Allergy to class/drug
	*Caution if:		*Caution if:
	**~~hypersens to sulfites~~		**sulfite hypersensitivity
	**renal impairment		**renal impairment, dehydration, concurrent nephrotoxic agent use
	**dehydration		**impaired auditory or vestibular function, concurrent ototoxic or neurotoxic agents
	**concurrent nephrotoxic agent use		**neuromuscular disease
	**impaired auditory ~~fun~~
	**impaired vestibular ~~fun~~
	**concurrent ototoxic ~~agent use~~
	**concurrent neurotoxic agents
	**neuromuscular dz
	**electrolyte abnormalities		**electrolyte abnormalities
	**prolonged use		**prolonged use, high dose treatment
	**high dose tx		**neonates/infants or elderly
	**neonates or ~~infants~~
	**elderly ~~pts~~

	==Adverse Reactions==		==Adverse Reactions==
			===Black Box Warnings===
			*Neurotoxicity/Ototoxicity
			**Increased risk with renal impairment, high dose, prolonged treatment
	===Serious===		===Serious===
	*Nephrotoxicity		*Nephrotoxicity
	*Ototoxicity, auditory		*Ototoxicity (auditory or vestibular)
	*Ototoxicity, vestibular		*Neurotoxicity, neuromuscular blockade
	*Neurotoxicity
	*Neuromuscular blockade
	===Common===		===Common===
	*Hearing loss		*Hearing loss, tinnitus, vertigo
	*Tinnitus
	*Vertigo
	*BUN, creatinine elevated		*BUN, creatinine elevated

Kaoru: /* Contraindications */

2016-09-28T17:17:13Z

Contraindications

@@ Línea 33: / Línea 33: @@
 ==Contraindications==
 *Allergy to class/drug
 ==Adverse Reactions==

Neil.m.young: Text replacement - "Cr " to "creatinine "

2016-08-11T09:28:28Z

Text replacement - "Cr " to "creatinine "

← Revisión anterior		Revisión del 09:28 11 ago 2016
Línea 45:		Línea 45:
	*Tinnitus		*Tinnitus
	*Vertigo		*Vertigo
	*BUN, Cr elevated		*BUN, creatinine elevated

	==Pharmacology==		==Pharmacology==

Neil.m.young: Text replacement - "5 mg" to "5mg"

2016-07-19T08:19:30Z

Text replacement - "5 mg" to "5mg"

← Revisión anterior		Revisión del 08:19 19 jul 2016
Línea 16:		Línea 16:

	==Adult Dosing==		==Adult Dosing==
	*Bacterial Infections: 7.~~5 mg~~/kg IM/IV q12h		*Bacterial Infections: 7.5mg/kg IM/IV q12h
	**For obese patients, use adjusted wt of IBW + 0.4 x (ABW - IBW)		**For obese patients, use adjusted wt of IBW + 0.4 x (ABW - IBW)
	**Adjust dose based on serum levels		**Adjust dose based on serum levels

	==Pediatric Dosing==		==Pediatric Dosing==
	*Bacterial Infections: 7.~~5 mg~~/kg IM/IV q12h		*Bacterial Infections: 7.5mg/kg IM/IV q12h

	==Special Populations==		==Special Populations==

Rossdonaldson1: Text replacement - "tx" to "treatment"

2016-07-14T04:15:53Z

Text replacement - "tx" to "treatment"

← Revisión anterior		Revisión del 04:15 14 jul 2016
Línea 6:		Línea 6:
	==Black Box Warnings==		==Black Box Warnings==
	*Neurotoxicity/Ototoxicity		*Neurotoxicity/Ototoxicity
	**Increased risk with renal impairment, high dose, prolonged tx		**Increased risk with renal impairment, high dose, prolonged treatment

	*Nephrotoxicity		*Nephrotoxicity
	**Increased risk with renal impairment, high dose, prolonged tx		**Increased risk with renal impairment, high dose, prolonged treatment
	**Monitor renal function, peak/trough levels		**Monitor renal function, peak/trough levels