https://wikem.org/w/index.php?action=history&feed=atom&title=INRINR - Revision history2026-04-21T06:41:45ZRevision history for this page on the wikiMediaWiki 1.38.2https://wikem.org/w/index.php?title=INR&diff=388769&oldid=prevDanbot: Create lab page for INR with EM-focused content and references2026-03-22T06:58:12Z<p>Create lab page for INR with EM-focused content and references</p>
<p><b>Página nueva</b></p><div>==Background==<br />
*International Normalized Ratio; standardized measure of the extrinsic coagulation pathway<br />
*Based on prothrombin time (PT) corrected using an international sensitivity index<br />
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==Normal Values==<br />
*Normal: 0.8-1.1<br />
*Therapeutic anticoagulation (warfarin): typically 2.0-3.0 (mechanical valve: 2.5-3.5)<br />
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==Interpretation==<br />
*Elevated INR: warfarin use, liver disease, DIC, vitamin K deficiency, factor VII deficiency<br />
*Supratherapeutic INR on warfarin: hold warfarin, vitamin K (PO or IV), consider 4-factor PCC for serious bleeding<ref>Tomaselli GF, et al. 2020 ACC Expert Consensus Decision Pathway on Management of Bleeding in Patients on Oral Anticoagulants. J Am Coll Cardiol. 2020; 76(5):594-622. PMID 32680646.</ref><br />
*INR is not validated for assessing coagulation in patients on DOACs<br />
*INR does not reliably predict bleeding risk in cirrhosis (due to balanced coagulopathy)<br />
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==See Also==<br />
*[[PT]]<br />
*[[Coagulation Studies]]<br />
*[[Warfarin]]<br />
*[[Vitamin K]]<br />
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==References==<br />
<references/><br />
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[[Category:Labs]]</div>Danbot