Ganciclovir - Revision history

Danbot: Restore original dosing content alongside dynamic SMW tables

2026-03-20T02:37:49Z

Restore original dosing content alongside dynamic SMW tables

← Revisión anterior		Revisión del 02:37 20 mar 2026
Línea 5:		Línea 5:

	==Adult Dosing==		==Adult Dosing==
			*[[CMV]] prophylaxis, solid organ transplant
			**IV route: 5mg/kg IV q12h x7-14 days, then 5mg/kg IV q24h or 6mg/kg IV 5x/wk
			**PO route: 1000mg PO tid, give with food

			*[[CMV]] prophylaxis, HIV-assoc.
			**IV route: 5mg/kg IV 5-7x/wk; Info: not 1st-line agent
			**PO route: 1000mg PO tid; Info: not 1st-line agent; give with food

			*[[CMV]] retinitis, immunocompromised patients
			**Induction treatment: 5mg/kg IV q12h x14-21 days; Info: not 1st-line agent
			**Maintenance treatment, IV route: 5mg/kg IV 5-7x/wk; Alt: 6mg/kg IV 5x/wk; Info: not 1st-line agent
			**Maintenance treatment, PO route: 1000mg PO tid; Alt: 500mg PO q3h while awake (6 doses/day); Info: not 1st-line agent; give with food


	===Indications by Disease===		===Indications by Disease===
	{{#ask: [[Has DrugName::Ganciclovir]] [[Has Population::Adult]]		{{#ask: [[Has DrugName::Ganciclovir]] [[Has Population::Adult]]
	\|?Treats disease=Disease		\|?Treats disease=Disease
	\|?Has Dose=Dose		\|?Has Dose=Dose
	\|?Has Context=Context		\|?Has Context=Context
	\|format=table		\|format=table
	\|limit=50		\|limit=50
	\|mainlabel=-		\|mainlabel=-
	\|headers=show		\|headers=show
	\|sort=Treats disease		\|sort=Treats disease
	}}		}}

	==Pediatric Dosing==		==Pediatric Dosing==
			''Off label use as pediatric medication''

			*[[CMV]] prophylaxis, solid organ transplant
			**Induction: 5mg/kg IV q12h x7-14 days
			**Maintenance: 5mg/kg IV q24h; Alt: 6mg/kg IV 5x/wk

			*[[CMV]] prophylaxis, HIV-assoc
			**5mg/kg IV q24h

			*[[CMV]] infection
			**Induction: 5mg/kg IV q12h x14-21 days; Info: may increase dose to 7.5mg/kg IV q12h
			**Maintenance: 5mg/kg IV q24h; Alt: 6mg/kg IV 5x/wk

			*[[CMV]] infection, congenital (<1 mo)
			**6mg/kg IV q12h x6wk


	===Indications by Disease===		===Indications by Disease===
	{{#ask: [[Has DrugName::Ganciclovir]] [[Has Population::Pediatric]]		{{#ask: [[Has DrugName::Ganciclovir]] [[Has Population::Pediatric]]
	\|?Treats disease=Disease		\|?Treats disease=Disease
	\|?Has Dose=Dose		\|?Has Dose=Dose
	\|?Has Context=Context		\|?Has Context=Context
	\|format=table		\|format=table
	\|limit=50		\|limit=50
	\|mainlabel=-		\|mainlabel=-
	\|headers=show		\|headers=show
	\|sort=Treats disease		\|sort=Treats disease
	}}		}}

Danbot: Replace manual dosing with dynamic SMW tables (Adult + Pediatric)

2026-03-20T01:52:45Z

Replace manual dosing with dynamic SMW tables (Adult + Pediatric)

← Revisión anterior		Revisión del 01:52 20 mar 2026
Línea 5:		Línea 5:

	==Adult Dosing==		==Adult Dosing==
	*[[~~CMV~~]] ~~prophylaxis, solid organ transplant~~		===Indications by Disease===
	**IV route: ~~5mg/kg IV q12h x7-14 days, then 5mg/kg IV q24h or 6mg/kg IV 5x/wk~~		{{#ask: [[Has DrugName::Ganciclovir]] [[Has Population::Adult]]
	**PO route: ~~1000mg PO tid, give with food~~		\|?Treats disease=Disease
			\|?Has Dose=Dose
	*[[CMV]] ~~prophylaxis, HIV-assoc.~~		\|?Has Context=Context
	**IV route: 5mg/kg IV 5-7x/wk; Info: not 1st-line agent		\|format=table
	**PO route: 1000mg PO tid; Info: not 1st-line agent; give with food		\|limit=50
			\|mainlabel=-
	*[[CMV]] retinitis, immunocompromised patients		\|headers=show
	**Induction treatment: 5mg/kg IV q12h x14-~~21 days; Info: not 1st-line agent~~		\|sort=Treats disease
	**Maintenance treatment, IV route: 5mg/kg IV 5-7x/wk; Alt: 6mg/kg IV 5x/wk; Info: not 1st-line agent		}}
	**Maintenance treatment, PO route: 1000mg PO tid; Alt: 500mg PO q3h while awake (6 doses/day); Info: not 1st-line agent; give with food

	==Pediatric Dosing==		==Pediatric Dosing==
	~~''Off label use as pediatric medication''~~		===Indications by Disease===
			{{#ask: [[Has DrugName::Ganciclovir]] [[Has Population::Pediatric]]
	*[[~~CMV~~]] ~~prophylaxis, solid organ transplant~~		\|?Treats disease=Disease
	**Induction: ~~5mg/kg IV q12h x7-14 days~~		\|?Has Dose=Dose
	**Maintenance: ~~5mg/kg IV q24h; Alt: 6mg/kg IV 5x/wk~~		\|?Has Context=Context
			\|format=table
	*[[CMV]] prophylaxis, HIV-assoc		\|limit=50
	**5mg/kg IV q24h		\|mainlabel=-
			\|headers=show
	*[[CMV]] infection		\|sort=Treats disease
	**Induction: 5mg/kg IV q12h x14-~~21 days; Info: may increase dose to 7.5mg/kg IV q12h~~		}}
	**Maintenance: 5mg/kg IV q24h; Alt: 6mg/kg IV 5x/wk

	*[[CMV]] infection, congenital (<1 mo)
	**6mg/kg IV q12h x6wk

	==Special Populations==		==Special Populations==

ClaireLewis: /* References */

2019-09-22T20:06:26Z

References

← Revisión anterior		Revisión del 20:06 22 sep 2019
Línea 83:		Línea 83:

	[[Category:Pharmacology]]		[[Category:Pharmacology]]
			[[Category:ID]]

ClaireLewis: /* Common */

2019-01-25T22:38:09Z

Common

← Revisión anterior		Revisión del 22:38 25 ene 2019
Línea 63:		Línea 63:
	*[[fever]]		*[[fever]]
	*[[leukopenia]]		*[[leukopenia]]
	*[[anorexia]]		*anorexia
	*[[vomiting]]		*[[vomiting]]

ELEE1987: /* Contraindications */

2017-10-13T15:11:12Z

Contraindications

← Revisión anterior		Revisión del 15:11 13 oct 2017
Línea 45:		Línea 45:
	==Contraindications==		==Contraindications==
	*Allergy to class/drug		*Allergy to class/drug
			* ANC < 500
			* Platelets < 25,000

	==Adverse Reactions==		==Adverse Reactions==

Mholtz: Text replacement - "qd" to "QD"

2017-07-07T11:30:49Z

Text replacement - "qd" to "QD"

← Revisión anterior		Revisión del 11:30 7 jul 2017
Línea 41:		Línea 41:
	*IV route, induction treatment: CrCl 50-69: 2.5mg/kg q12h; CrCl 25-49: 2.5mg/kg q24h; CrCl 10-24: 1.25mg/kg q24h; CrCl <10: 1.25mg/kg 3x/wk; HD: give dose after dialysis, no supplement		*IV route, induction treatment: CrCl 50-69: 2.5mg/kg q12h; CrCl 25-49: 2.5mg/kg q24h; CrCl 10-24: 1.25mg/kg q24h; CrCl <10: 1.25mg/kg 3x/wk; HD: give dose after dialysis, no supplement
	*IV route, maintenance treatment: CrCl 50-69: 2.5mg/kg q24h; CrCl 25-49: 1.25mg/kg q24h; CrCl 10-24: 0.625mg/kg q24h; CrCl <10: 0.625mg/kg 3x/wk; HD: give dose after dialysis, no supplement		*IV route, maintenance treatment: CrCl 50-69: 2.5mg/kg q24h; CrCl 25-49: 1.25mg/kg q24h; CrCl 10-24: 0.625mg/kg q24h; CrCl <10: 0.625mg/kg 3x/wk; HD: give dose after dialysis, no supplement
	*PO route: CrCl 50-69: 1500mg/day divided qd-tid; CrCl 25-49: 1000mg/day divided qd-bid; CrCl 10-24: 500mg qd; CrCl <10: 500mg 3x/wk; HD: give dose after dialysis, no supplement		*PO route: CrCl 50-69: 1500mg/day divided QD-tid; CrCl 25-49: 1000mg/day divided QD-bid; CrCl 10-24: 500mg QD; CrCl <10: 500mg 3x/wk; HD: give dose after dialysis, no supplement

	==Contraindications==		==Contraindications==

ClaireLewis: /* Special Populations */

2017-02-25T22:39:06Z

Special Populations

← Revisión anterior		Revisión del 22:39 25 feb 2017
Línea 36:		Línea 36:

	==Special Populations==		==Special Populations==
	*[[Drug Ratings in Pregnancy\|Pregnancy Rating]]:		*[[Drug Ratings in Pregnancy\|Pregnancy Rating]]: C
	*[[Lactation risk categories\|Lactation risk]]:		*[[Lactation risk categories\|Lactation risk]]: Infant risk cannot be ruled out
	===Renal Dosing===		===Renal Dosing===
	*IV route, induction treatment: CrCl 50-69: 2.5mg/kg q12h; CrCl 25-49: 2.5mg/kg q24h; CrCl 10-24: 1.25mg/kg q24h; CrCl <10: 1.25mg/kg 3x/wk; HD: give dose after dialysis, no supplement		*IV route, induction treatment: CrCl 50-69: 2.5mg/kg q12h; CrCl 25-49: 2.5mg/kg q24h; CrCl 10-24: 1.25mg/kg q24h; CrCl <10: 1.25mg/kg 3x/wk; HD: give dose after dialysis, no supplement

ClaireLewis: /* Contraindications */

2017-02-25T22:38:30Z

Contraindications

← Revisión anterior		Revisión del 22:38 25 feb 2017
Línea 45:		Línea 45:
	==Contraindications==		==Contraindications==
	*Allergy to class/drug		*Allergy to class/drug
	*hypersens. to acyclovir
	*ANC <500
	*Platlet <25,000

	==Adverse Reactions==		==Adverse Reactions==

ClaireLewis: /* Administration */

2017-02-25T22:36:22Z

Administration

← Revisión anterior		Revisión del 22:36 25 feb 2017
Línea 1:		Línea 1:
	==Administration==		==Administration==
	*Type: Antiviral		*Type: [[Antiviral]]
	*Routes of Administration: IV, PO		*Routes of Administration: IV, PO
	*Common Trade Names: Cytovene		*Common Trade Names: Cytovene

Rossdonaldson1: Text replacement - "Plt " to "Platlet "

2016-08-31T16:23:30Z

Text replacement - "Plt " to "Platlet "

← Revisión anterior		Revisión del 16:23 31 ago 2016
Línea 47:		Línea 47:
	*hypersens. to acyclovir		*hypersens. to acyclovir
	*ANC <500		*ANC <500
	*~~Plt~~ <25,000		*Platlet <25,000

	==Adverse Reactions==		==Adverse Reactions==