Eosinophilic granulomatosis with polyangiitis - Revision history

Rossdonaldson1: /* Background */

2023-08-02T17:44:25Z

Background

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	==Background==		==Background==
	*Formerly known as Churg-Strauss ~~syndrome~~		*Formerly known as Churg-Strauss Syndrome
	*Chronic [[sinusitis]], [[asthma]], and peripheral [[eosinophilia]]		*Chronic [[sinusitis]], [[asthma]], and peripheral [[eosinophilia]]
	*Vasculitis of small and medium sized vessels		*Vasculitis of small and medium sized vessels
	*Lung and skin are most commonly involved		*Lung and skin are most commonly involved

			{{Primary Vasculitis DDX}}

	==Clinical Features==		==Clinical Features==

Elcatracho: /* See Also */

2021-03-08T19:53:21Z

Elcatracho: /* See Also */

2021-03-08T19:44:16Z

ClaireLewis: /* Maintenance Therapy */

2019-10-17T23:39:09Z

Maintenance Therapy

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	*[[Methotrexate]]		*[[Methotrexate]]
	*Leflunomide		*Leflunomide
	*[[Inhaled ~~corticosteroids~~]]		*[[Inhaled corticosteroid]]s

	==Disposition==		==Disposition==

ClaireLewis at 23:38, 17 October 2019

2019-10-17T23:38:53Z

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	Classically develops in three sequential phases:		Classically develops in three sequential phases:
	#Prodrome		#Prodrome
	#*Atopic diseases, allergic rhinitis, and asthma		#*Atopic diseases, [[allergic rhinitis]], and [[asthma]]
	#Eosinophilic phase		#Eosinophilic phase
	#*Multiorgan involvement, particularly lung and GI tract		#*Multiorgan involvement, particularly lung and GI tract
	#*Caused by eosinophilic infiltration into these organs		#*Caused by eosinophilic infiltration into these organs
	#Vasculitic phase		#Vasculitic phase
	#*Life threatening vasculitis associated with vascular and extravascular granulomatosis		#*Life threatening [[vasculitis]] associated with vascular and extravascular granulomatosis
	#*May present with nonspecific signs such as fever, weight loss, malaise		#*May present with nonspecific signs such as [[fever]], weight loss, malaise

	==Differential Diagnosis==		==Differential Diagnosis==
	*Aspirin-exacerbated respiratory disease		*[[Aspirin]]-exacerbated respiratory disease
	*Chronic eosinophilic pneumonia		*Chronic eosinophilic pneumonia
	*Allergic bronchopulmonary aspergillosis		*Allergic bronchopulmonary [[aspergillosis]]
	*Hypereosinophilic syndrome		*Hypereosinophilic syndrome
	*Other [[vasculitis syndromes]]		*Other [[vasculitis syndromes]]
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	*[[Methotrexate]]		*[[Methotrexate]]
	*Leflunomide		*Leflunomide
	*Inhaled ~~glucocorticoids~~		*[[Inhaled corticosteroids]]

	==Disposition==		==Disposition==

Mholtz at 03:34, 30 December 2016

2016-12-30T03:34:46Z

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	==Management==		==Management==
	===~~Initiation~~ Therapy===		===Acute Therapy===
	*[[Prednisone]] 0.5-1.5mg/kg/day		*[[Prednisone]] 0.5-1.5mg/kg/day
	*[[Cyclophosphamide]]		*[[Cyclophosphamide]]
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	==References==		==References==
			<references/>

	[[Category:Rheumatology]]		[[Category:Rheumatology]]

ClaireLewis: Created page with "==Background== Formerly known as Churg-Strauss syndrome Chronic sinusitis, asthma, and peripheral eosinophilia Vasculitis of small and medium sized vessels Lun..."

2016-11-13T03:36:55Z

Created page with "==Background== *Formerly known as Churg-Strauss syndrome *Chronic sinusitis, asthma, and peripheral eosinophilia *Vasculitis of small and medium sized vessels *Lun..."

Página nueva

==Background==
*Formerly known as Churg-Strauss syndrome
*Chronic [[sinusitis]], [[asthma]], and peripheral [[eosinophilia]]
*Vasculitis of small and medium sized vessels
*Lung and skin are most commonly involved

==Clinical Features==
Classically develops in three sequential phases:
#Prodrome
#*Atopic diseases, allergic rhinitis, and asthma
#Eosinophilic phase
#*Multiorgan involvement, particularly lung and GI tract
#*Caused by eosinophilic infiltration into these organs
#Vasculitic phase
#*Life threatening vasculitis associated with vascular and extravascular granulomatosis
#*May present with nonspecific signs such as fever, weight loss, malaise

==Differential Diagnosis==
*Aspirin-exacerbated respiratory disease
*Chronic eosinophilic pneumonia
*Allergic bronchopulmonary aspergillosis
*Hypereosinophilic syndrome
*Other [[vasculitis syndromes]]

==Evaluation==
*Typically a clinical diagnosis
*Labs with elevated eosinophils, ESR, CRP, ANCA
*[[CXR]] with transient, patchy opacities

==Management==
===Initiation Therapy===
*[[Prednisone]] 0.5-1.5mg/kg/day
*[[Cyclophosphamide]]

===Maintenance Therapy===
*[[Azathioprine]]
*[[Methotrexate]]
*Leflunomide
*Inhaled glucocorticoids

==Disposition==
*Refer to rheumatology

==See Also==

==External Links==

==References==

[[Category:Rheumatology]]

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	==See Also==		==See Also==
	*[[Vasculitis syndromes]]		*[[Vasculitis syndromes]]
			*[[Granulomatosis with polyangiitis]]

	==External Links==		==External Links==

← Revisión anterior		Revisión del 19:44 8 mar 2021
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	==See Also==		==See Also==
			*[[Vasculitis syndromes]]

	==External Links==		==External Links==

Eosinophilic granulomatosis with polyangiitis - Revision history

Rossdonaldson1: /* Background */

Elcatracho: /* See Also */

Elcatracho: /* See Also */

ClaireLewis: /* Maintenance Therapy */

ClaireLewis at 23:38, 17 October 2019

Mholtz at 03:34, 30 December 2016

ClaireLewis: Created page with "==Background== *Formerly known as Churg-Strauss syndrome *Chronic sinusitis, asthma, and peripheral eosinophilia *Vasculitis of small and medium sized vessels *Lun..."

ClaireLewis: Created page with "==Background== Formerly known as Churg-Strauss syndrome Chronic sinusitis, asthma, and peripheral eosinophilia Vasculitis of small and medium sized vessels Lun..."