Cor pulmonale - Revision history

Danbot: Add verified PubMed references (PMIDs 32088063)

2026-03-22T10:59:12Z

Add verified PubMed references (PMIDs 32088063)

← Revisión anterior		Revisión del 10:59 22 mar 2026
Línea 1:		Línea 1:
	==Background==		==Background==
	*Remodeling of right ventricle in response to pulmonary pathology		*Remodeling of right ventricle in response to pulmonary pathology<ref>Aubry A, Paternot A, Vieillard-Baron A. [Cor pulmonale]. Rev Mal Respir. 2020 Mar;37(3):257-266. PMID 32088063</ref>
	*Often caused by [[COPD]], [[pulmonary hypertension]], [[PE]], [[ARDS]]		*Often caused by [[COPD]], [[pulmonary hypertension]], [[PE]], [[ARDS]]

Cmb23: /* ECG */

2023-09-28T00:51:51Z

ECG

← Revisión anterior		Revisión del 00:51 28 sep 2023
Línea 56:		Línea 56:
	*[[Right bundle branch block]]		*[[Right bundle branch block]]
	*R:S ratio > 1 in V1		*R:S ratio > 1 in V1
	*TWI in V1-3 in acute right heart strain		*TWI in V1-3 in acute right heart strain (as opposed to upright t-waves in posterior MI)
	*S1 Q3 T3 in acute right heart strain		*S1 Q3 T3 in acute right heart strain
	*Large P wave in II, III, aVF		*Large P wave in II, III, aVF

ClaireLewis at 15:15, 12 October 2019

2019-10-12T15:15:00Z

← Revisión anterior		Revisión del 15:15 12 oct 2019
Línea 35:		Línea 35:
	**[[pneumonia]]		**[[pneumonia]]
	*Other		*Other
	**Pure volume overload		**Pure [[fluid overload\|volume overload]]
	***[[Renal Failure]]		***[[Renal Failure]]
	***Post-[[Transfusion]]		***Post-[[Transfusion]]
Línea 42:		Línea 42:
	==Evaluation==		==Evaluation==
	===Blood tests===		===Blood tests===
	*CBC (polycythemia)		*CBC ([[polycythemia]])
	*[[ABG]] (oxygenation, acid-base status)		*[[ABG]] (oxygenation, acid-base status)
	*α-1-antitrypsin		*α-1-antitrypsin
Línea 59:		Línea 59:
	*S1 Q3 T3 in acute right heart strain		*S1 Q3 T3 in acute right heart strain
	*Large P wave in II, III, aVF		*Large P wave in II, III, aVF
	*[[Arrhythmia]] ([[PAC]], [[SVT]], MFAT, [[A-fib]], [[A-flutter]])		*[[Arrhythmia]] ([[PAC]], [[SVT]], MFAT, [[A-fib]], A-[[flutter]])

	===[[Echocardiography]]===		===[[Echocardiography]]===

ClaireLewis at 18:36, 24 September 2019

2019-09-24T18:36:14Z

← Revisión anterior		Revisión del 18:36 24 sep 2019
Línea 5:		Línea 5:
	==Clinical Features==		==Clinical Features==
	===Pathophysiology===		===Pathophysiology===
	*Pulmonary vasoconstriction (hypoxia, acidemia)		*Pulmonary vasoconstriction ([[hypoxia]], [[acidosis\|acidemia]])
	*Destruction of pulmonary vasculature by emphysema, ~~ILD~~		*Destruction of pulmonary vasculature by emphysema, [[interstitial lung disease]]
	*Increased blood viscosity ([[sickle cell disease]], polycythemia)		*Increased blood viscosity ([[sickle cell disease]], [[polycythemia]])
	===Chronic===		===Chronic===
	*[[RVH]]		*[[RVH]]
Línea 26:		Línea 26:
	**[[Acute Valve Dysfunction]]		**[[Acute Valve Dysfunction]]
	**[[Aortic Dissection]]		**[[Aortic Dissection]]
	**[[~~Dysrhthymia~~]]		**[[Dysrhythmia]]
	**[[Endocarditis]]		**[[Endocarditis]]
	**[[Hypertensive Emergency]]		**[[Hypertensive Emergency]]
Línea 43:		Línea 43:
	===Blood tests===		===Blood tests===
	*CBC (polycythemia)		*CBC (polycythemia)
	*ABG (oxygenation, acid-base status)		*[[ABG]] (oxygenation, acid-base status)
	*α-1-antitrypsin		*α-1-antitrypsin
	*ANA		*ANA
	*Coagulation studies (protein C/S, factor V Leiden etc)		*Coagulation studies (protein C/S, factor V Leiden etc)
	===CXR===		===[[CXR]]===
	*Enlarged pulmonary arteries		*Enlarged pulmonary arteries
	*Cardiomegaly		*Cardiomegaly
	*Decreased retrosternal air space		*Decreased retrosternal air space
	===ECG===		===[[ECG]]===
	*[[RVH]]		*[[RVH]]
	*Right axis deviation		*Right axis deviation
Línea 59:		Línea 59:
	*S1 Q3 T3 in acute right heart strain		*S1 Q3 T3 in acute right heart strain
	*Large P wave in II, III, aVF		*Large P wave in II, III, aVF
	*Arrhythmia (PAC, SVT, MFAT, A-fib, A-flutter)		*[[Arrhythmia]] ([[PAC]], [[SVT]], MFAT, [[A-fib]], [[A-flutter]])

	===~~Echo~~===		===[[Echocardiography]]===
	*Increased RV thickness		*Increased RV thickness
	*RV dilation		*RV dilation
Línea 72:		Línea 72:
	==Management==		==Management==
	*Treat underlying disease		*Treat underlying disease
	*Fluids, vasoconstrictors to support BP in acute setting		*Fluids, [[vasopressors\|vasoconstrictors]] to support BP in acute setting
	*Oxygen therapy: decreases pulmonary vasoconstriction		*[[Oxygen therapy]]: decreases pulmonary vasoconstriction
	*Diuretics: decrease RV filling volume		*[[Diuretics]]: decrease RV filling volume
	*[[Calcium channel blockers]]: vasodilate the pulmonary arteries		*[[Calcium channel blockers]]: vasodilate the pulmonary arteries
	*Beta agonists (epoprostenol, iloprost): bronchodilate		*Beta agonists ([[epoprostenol]], iloprost): bronchodilate
	*Phlebotomy for severe hypoxia leading to polycythemia		*Phlebotomy for severe hypoxia leading to polycythemia
	*Lung transplant or heart-lung transplant as last resort		*Lung transplant or heart-lung transplant as last resort

Neil.m.young: Text replacement - "alpha" to "α"

2017-07-24T01:12:27Z

Text replacement - "alpha" to "α"

← Revisión anterior		Revisión del 01:12 24 jul 2017
Línea 44:		Línea 44:
	*CBC (polycythemia)		*CBC (polycythemia)
	*ABG (oxygenation, acid-base status)		*ABG (oxygenation, acid-base status)
	*~~alpha~~-1-antitrypsin		*α-1-antitrypsin
	*ANA		*ANA
	*Coagulation studies (protein C/S, factor V Leiden etc)		*Coagulation studies (protein C/S, factor V Leiden etc)

Neil.m.young at 16:24, 1 March 2017

2017-03-01T16:24:27Z

← Revisión anterior		Revisión del 16:24 1 mar 2017
Línea 56:		Línea 56:
	*[[Right bundle branch block]]		*[[Right bundle branch block]]
	*R:S ratio > 1 in V1		*R:S ratio > 1 in V1
	*TWI in V1-3 in acute ~~rightheart~~ strain		*TWI in V1-3 in acute right heart strain
	*S1 Q3 T3 in acute ~~rightheart~~ strain		*S1 Q3 T3 in acute right heart strain
	*Large P wave in II, III, aVF		*Large P wave in II, III, aVF
	*Arrhythmia (PAC, SVT, MFAT, A-fib, A-flutter)		*Arrhythmia (PAC, SVT, MFAT, A-fib, A-flutter)

Neil.m.young: Text replacement - " R " to " right"

2017-02-27T22:53:18Z

Text replacement - " R " to " right"

← Revisión anterior		Revisión del 22:53 27 feb 2017
Línea 56:		Línea 56:
	*[[Right bundle branch block]]		*[[Right bundle branch block]]
	*R:S ratio > 1 in V1		*R:S ratio > 1 in V1
	*TWI in V1-3 in acute ~~R heart~~ strain		*TWI in V1-3 in acute rightheart strain
	*S1 Q3 T3 in acute ~~R heart~~ strain		*S1 Q3 T3 in acute rightheart strain
	*Large P wave in II, III, aVF		*Large P wave in II, III, aVF
	*Arrhythmia (PAC, SVT, MFAT, A-fib, A-flutter)		*Arrhythmia (PAC, SVT, MFAT, A-fib, A-flutter)

Neil.m.young: Text replacement - "==Diagnosis==" to "==Evaluation=="

2016-07-23T20:31:54Z

Text replacement - "==Diagnosis==" to "==Evaluation=="

← Revisión anterior		Revisión del 20:31 23 jul 2016
Línea 40:		Línea 40:
	**[[Sepsis]]		**[[Sepsis]]

	==~~Diagnosis~~==		==Evaluation==
	===Blood tests===		===Blood tests===
	*CBC (polycythemia)		*CBC (polycythemia)

Rossdonaldson1: Text replacement - "PNA" to "pneumonia"

2016-07-18T16:04:11Z

Text replacement - "PNA" to "pneumonia"

← Revisión anterior		Revisión del 16:04 18 jul 2016
Línea 33:		Línea 33:
	**[[COPD]]		**[[COPD]]
	**[[PE]]		**[[PE]]
	**[[~~PNA~~]]		**[[pneumonia]]
	*Other		*Other
	**Pure volume overload		**Pure volume overload

Alvarez13 at 00:28, 19 May 2016

2016-05-19T00:28:43Z

← Revisión anterior		Revisión del 00:28 19 may 2016
Línea 84:		Línea 84:

	==See Also==		==See Also==
	[[Pulmonary Embolism]]		*[[Pulmonary Embolism]]
	[[COPD]]		*[[COPD]]

	==External Links==		==External Links==