Cefepime - Revision history

Danbot: Remove disease-specific entries now covered by AntibioticDose (3 sections)

2026-03-20T11:07:57Z

Remove disease-specific entries now covered by AntibioticDose (3 sections)

← Revisión anterior		Revisión del 11:07 20 mar 2026
Línea 10:		Línea 10:
	*1-2 g IV q12H (Max: 6 g/24h; dose, duration varies with infection type, severity)		*1-2 g IV q12H (Max: 6 g/24h; dose, duration varies with infection type, severity)

	~~===Febrile Neutropenia===~~
	*2g IV q8H

	===Renal dosing===		===Renal dosing===
Línea 41:		Línea 39:
	*>2 mo: Dose: 50mg/kg IV/IM q12h; Max: 2 g/dose; Info: duration varies with infection type, severity; IM only for mild-mod. UTI due to E. coli		*>2 mo: Dose: 50mg/kg IV/IM q12h; Max: 2 g/dose; Info: duration varies with infection type, severity; IM only for mild-mod. UTI due to E. coli

	~~===Febrile Neutropenia===~~
	*>2 mo: Dose: 50mg/kg IV q8h; Max: 2 g/dose

	~~===Respiratory Infections, cystic fibrosis patients===~~
	*>2 mo: Dose: 50mg/kg IV q8h x2wk; Max: 2 g/dose

	===Renal Dosing===		===Renal Dosing===

Danbot: Remove disease-specific dosing covered by dynamic SMW tables

2026-03-20T02:57:34Z

Remove disease-specific dosing covered by dynamic SMW tables

← Revisión anterior		Revisión del 02:57 20 mar 2026
Línea 12:		Línea 12:
	===Febrile Neutropenia===		===Febrile Neutropenia===
	*2g IV q8H		*2g IV q8H

	~~===[[UTI]], mild-moderate===~~
	*0.5-1g IV/IM q12H x7-10 days (IM only for UTI due to E. coli)

	~~===[[UTI]], severe===~~
	*2g IV q12H x10 days

	===Renal dosing===		===Renal dosing===

Danbot: Restore original dosing content alongside dynamic SMW tables

2026-03-20T02:37:26Z

Restore original dosing content alongside dynamic SMW tables

← Revisión anterior		Revisión del 02:37 20 mar 2026
Línea 7:		Línea 7:

	==Adult Dosing==		==Adult Dosing==
			===Bacterial Infections===
			*1-2 g IV q12H (Max: 6 g/24h; dose, duration varies with infection type, severity)

			===Febrile Neutropenia===
			*2g IV q8H

			===[[UTI]], mild-moderate===
			*0.5-1g IV/IM q12H x7-10 days (IM only for UTI due to E. coli)

			===[[UTI]], severe===
			*2g IV q12H x10 days

			===Renal dosing===
			*Febrile Neutropenia: CrCl 30-60: 2 g q12H; CrCl 11-29: 2 g q24H; CrCL <11: 2gx1, then 1g q24H; HD: 1g q24H, give after dialysis; PD: 2g q48H
			*All other infections: CrCl 30-60: give q24h; CrCl 11-29: give usual dose x1, then 0.5-1 g q24h; CrCl <11: give usual dose x1, then 250-500mg q24h; HD: 1 g x1, then 500mg q24h, give after dialysis; PD: give usual dose q48h

			===Hepatic Dosing===
			*no adjustment


	===Indications by Disease===		===Indications by Disease===
	{{#ask: [[Has DrugName::Cefepime]] [[Has Population::Adult]]		{{#ask: [[Has DrugName::Cefepime]] [[Has Population::Adult]]
	\|?Treats disease=Disease		\|?Treats disease=Disease
	\|?Has Dose=Dose		\|?Has Dose=Dose
	\|?Has Context=Context		\|?Has Context=Context
	\|format=table		\|format=table
	\|limit=50		\|limit=50
	\|mainlabel=-		\|mainlabel=-
	\|headers=show		\|headers=show
	\|sort=Treats disease		\|sort=Treats disease
	}}		}}

	==Pediatric Dosing==		==Pediatric Dosing==
			*Mild to moderate infection: 50 mg/kg/dose every 12 hours; maximum dose: 2,000 mg/dose

			*Severe infection: 50 mg/kg/dose every 8 to 12 hours; maximum dose: 2,000 mg/dose

			===Bacterial Infections===
			*>2 mo: Dose: 50mg/kg IV/IM q12h; Max: 2 g/dose; Info: duration varies with infection type, severity; IM only for mild-mod. UTI due to E. coli

			===Febrile Neutropenia===
			*>2 mo: Dose: 50mg/kg IV q8h; Max: 2 g/dose

			===Respiratory Infections, cystic fibrosis patients===
			*>2 mo: Dose: 50mg/kg IV q8h x2wk; Max: 2 g/dose

			===Renal Dosing===
			*Febrile Neutropenia, cystic fibrosis: CrCl 30-60: 50mg/kg q12h; CrCl 11-29: 50mg/kg q24h; CrCl <11: 50mg/kg x1, then 25mg/kg q24h; HD: 25mg/kg q24h, give after dialysis; PD: 50mg/kg q48h
			*all other infections: CrCl 30-60: 50mg/kg q24h; CrCl 11-29: 50mg/kg x1, then 25-50mg/kg q24h; CrCl <11: 50mg/kg x1, then 12.5-25mg/kg q24h; HD: 50mg/kg x1, then 25mg/kg q24h, give after dialysis; PD: 50mg/kg q48h

			===Hepatic Dosing===
			*No Adjustment


	===Indications by Disease===		===Indications by Disease===
	{{#ask: [[Has DrugName::Cefepime]] [[Has Population::Pediatric]]		{{#ask: [[Has DrugName::Cefepime]] [[Has Population::Pediatric]]
	\|?Treats disease=Disease		\|?Treats disease=Disease
	\|?Has Dose=Dose		\|?Has Dose=Dose
	\|?Has Context=Context		\|?Has Context=Context
	\|format=table		\|format=table
	\|limit=50		\|limit=50
	\|mainlabel=-		\|mainlabel=-
	\|headers=show		\|headers=show
	\|sort=Treats disease		\|sort=Treats disease
	}}		}}

Danbot: Replace manual dosing with dynamic SMW tables (Adult + Pediatric)

2026-03-20T01:52:04Z

Replace manual dosing with dynamic SMW tables (Adult + Pediatric)

← Revisión anterior		Revisión del 01:52 20 mar 2026
Línea 7:		Línea 7:

	==Adult Dosing==		==Adult Dosing==
	===~~Bacterial Infections~~===		===Indications by Disease===
	*1-2 g IV q12H (Max: ~~6 g/24h; dose, duration varies with infection type, severity)~~		{{#ask: [[Has DrugName::Cefepime]] [[Has Population::Adult]]
			\|?Treats disease=Disease
	~~===Febrile Neutropenia===~~		\|?Has Dose=Dose
	*2g IV q8H		\|?Has Context=Context
			\|format=table
	~~===~~[[~~UTI~~]]~~, mild-moderate===~~		\|limit=50
	*0.5-1g IV/IM q12H x7-10 days (IM only for UTI due to E. coli)		\|mainlabel=-
			\|headers=show
	~~===~~[[~~UTI~~]]~~, severe~~===		\|sort=Treats disease
	*2g IV q12H x10 days		}}

	=~~==Renal dosing===~~
	*Febrile Neutropenia: CrCl 30-60: 2 g q12H; CrCl 11-~~29: 2 g q24H; CrCL <11: 2gx1, then 1g q24H; HD: 1g q24H, give after dialysis; PD: 2g q48H~~
	*All other infections: CrCl 30-60: give q24h; CrCl 11-29: give usual dose x1, then 0.5-1 g q24h; CrCl <11: give usual dose x1, then 250-500mg q24h; HD: 1 g x1, then 500mg q24h, give after dialysis; PD: give usual dose q48h

	=~~==Hepatic Dosing===~~
	*no adjustment

	==Pediatric Dosing==		==Pediatric Dosing==
	*Mild to moderate infection: 50 mg/kg/dose every 12 hours; maximum dose: 2,000 mg/dose		===Indications by Disease===
			{{#ask: [[Has DrugName::Cefepime]] [[Has Population::Pediatric]]
	*Severe infection: 50 mg/kg/dose every 8 to 12 hours; maximum dose: 2,000 mg/dose		\|?Treats disease=Disease
			\|?Has Dose=Dose
	===~~Bacterial Infections~~===		\|?Has Context=Context
	*>2 mo: ~~Dose~~: ~~50mg/kg IV/IM q12h; Max~~: ~~2 g/dose; Info~~: ~~duration varies with infection type, severity; IM only for mild-mod. UTI due to E. coli~~		\|format=table
			\|limit=50
	=~~==Febrile Neutropenia===~~		\|mainlabel=-
	*>2 mo: Dose~~: 50mg/kg IV q8h; Max: 2 g/dose~~		\|headers=show
			\|sort=Treats disease
	~~===Respiratory Infections, cystic fibrosis patients==~~=		}}
	*>2 mo: Dose~~: 50mg/kg IV q8h x2wk; Max: 2 g/dose~~

	===~~Renal Dosing===~~
	*Febrile Neutropenia, cystic fibrosis: CrCl 30-60: 50mg/kg q12h; CrCl 11-~~29: 50mg/kg q24h; CrCl <11: 50mg/kg x1, then 25mg/kg q24h; HD: 25mg/kg q24h, give after dialysis; PD: 50mg/kg q48h~~
	*all other infections: CrCl 30-60: 50mg/kg q24h; CrCl 11-29: 50mg/kg x1, then 25-50mg/kg q24h; CrCl <11: 50mg/kg x1, then 12.5-25mg/kg q24h; HD: 50mg/kg x1, then 25mg/kg q24h, give after dialysis; PD: 50mg/kg q48h

	=~~==Hepatic Dosing===~~
	*No Adjustment

	==Special Populations==		==Special Populations==

Ostermayer at 18:14, 18 July 2025

2025-07-18T18:14:40Z

← Revisión anterior		Revisión del 18:14 18 jul 2025
Línea 171:		Línea 171:
	\| \|\|[[Acinetobacter sp.]]\|\|I		\| \|\|[[Acinetobacter sp.]]\|\|I
	\|-		\|-
	\| \|\|[[Pseudomonas aeruginosa]]\|\|'''S'''		\| \|\|[[Pseudomonas aeruginosa]]\|\|'''[[Has Antipseudomonal::S]]'''
	\|-		\|-
	\| \|\|[[Burkholderia cepacia]]\|\|I		\| \|\|[[Burkholderia cepacia]]\|\|I

Ostermayer at 16:21, 18 July 2025

2025-07-18T16:21:46Z

← Revisión anterior		Revisión del 16:21 18 jul 2025
Línea 1:		Línea 1:
	==General==		==General==
	*Type: ~~Fourth~~ generation [[Is DrugClass::cephalosporins]]		*Type: [[Is Generation::4th generation]] [[Is DrugClass::cephalosporins]]
	*Dosage Forms: infusion solution, powder for injection		*Dosage Forms: infusion solution, powder for injection
	*Dosage Strengths: infusion solution: 1g/50mL, 2g/100mL; powder for injection: 1g, 2g		*Dosage Strengths: infusion solution: 1g/50mL, 2g/100mL; powder for injection: 1g, 2g

Ostermayer at 14:52, 18 July 2025

2025-07-18T14:52:26Z

← Revisión anterior		Revisión del 14:52 18 jul 2025
Línea 1:		Línea 1:
	==General==		==General==
	*Type: Fourth generation [[~~Cephalosporins\|cephalosporin~~]]		*Type: Fourth generation [[Is DrugClass::cephalosporins]]
	*Dosage Forms: infusion solution, powder for injection		*Dosage Forms: infusion solution, powder for injection
	*Dosage Strengths: infusion solution: 1g/50mL, 2g/100mL; powder for injection: 1g, 2g		*Dosage Strengths: infusion solution: 1g/50mL, 2g/100mL; powder for injection: 1g, 2g

Elcatracho: /* Serious */

2021-02-21T01:28:45Z

Serious

← Revisión anterior		Revisión del 01:28 21 feb 2021
Línea 67:		Línea 67:
	===Serious===		===Serious===
	*[[Anaphylaxis]]		*[[Anaphylaxis]]
	*[[Encephalopathy]]		*[[Encephalopathy]] (patients with renal insufficiency more prone)
	*[[Seizures]]		*[[Seizures]]
	*Non-convulsive status epilepticus		*Non-convulsive status epilepticus

Robyn.levine: /* References */

2019-09-04T20:49:07Z

References

← Revisión anterior		Revisión del 20:49 4 sep 2019
Línea 224:		Línea 224:
	<references/>		<references/>
	[[Category:Pharmacology]]		[[Category:Pharmacology]]

			*Lexicomp
			Accessed September 4, 2019

Robyn.levine: /* Pediatric Dosing */

2019-09-04T20:47:44Z

Pediatric Dosing

← Revisión anterior		Revisión del 20:47 4 sep 2019
Línea 27:		Línea 27:

	==Pediatric Dosing==		==Pediatric Dosing==
			*Mild to moderate infection: 50 mg/kg/dose every 12 hours; maximum dose: 2,000 mg/dose

			*Severe infection: 50 mg/kg/dose every 8 to 12 hours; maximum dose: 2,000 mg/dose

	===Bacterial Infections===		===Bacterial Infections===