Campylobacter jejuni - Revision history

Kxl328: /* Background */

2018-10-12T01:46:39Z

Background

← Revisión anterior		Revisión del 01:46 12 oct 2018
Línea 4:		Línea 4:
	*Caused by oral-fecal transmission		*Caused by oral-fecal transmission
	*Associated with [[Guillain-Barre syndrome]] and [[Reactive arthritis\|Reiter syndrome]]		*Associated with [[Guillain-Barre syndrome]] and [[Reactive arthritis\|Reiter syndrome]]
			*Incubation period of about 2-5 days, with duration of illness around 2-10 days<ref>U.S. Dept of Health and Human Services. Campylobacter. https://www.foodsafety.gov/poisoning/causes/bacteriaviruses/campylobacter/index.html</ref>

	==Clinical Features==		==Clinical Features==

Mholtz at 06:20, 25 September 2018

2018-09-25T06:20:15Z

← Revisión anterior		Revisión del 06:20 25 sep 2018
Línea 34:		Línea 34:

	==Evaluation==		==Evaluation==
	*~~Initiate~~ work up ~~in patients~~:		''Not every patient with fever and diarrhea requires work-up - use clinical judgement''
	**~~Appearing toxic~~
	**~~Febrile~~		*Consider work-up for patient with:
	**~~Diarrheal illness~~ lasting >3 days		**Fever
			**Toxic appearance
			**Diarrhea lasting >3 days
	**Blood or pus in stool		**Blood or pus in stool
	**Immunocompromised patients with presumed infectious diarrhea		**Immunocompromised patients with presumed infectious diarrhea
	*Bacterial stool culture		*Bacterial stool culture
			**N.B. - In many labs, stool culture tests for [[Salmonella]], [[Shigella]], and [[Campylobacter]]
	*Stool ova and parasites if concern for parasitic infection		*Stool ova and parasites if concern for parasitic infection
	*Consider [[C. difficile]] PCR if patient has risk factors		*Consider [[C. difficile]] PCR if patient has risk factors
	*Note- in many labs, stool culture tests for [[Salmonella]], [[Shigella]], and [[Campylobacter]]; discuss with your lab for further testing
	*Note- not every patient with fever and diarrhea needs work up, use clinical judgment

	==Management<ref>http://www.cdc.gov/nczved/divisions/dfbmd/diseases/campylobacter/#treat</ref>==		==Management<ref>http://www.cdc.gov/nczved/divisions/dfbmd/diseases/campylobacter/#treat</ref>==
	*Fluid resuscitation- oral rehydration therapy preferred		*Fluid resuscitation - oral rehydration therapy preferred
	*Avoid antimotility agents with bloody diarrhea		*Avoid antimotility agents with bloody diarrhea
	*Many recover without antimicrobial therapy		*Many recover without antimicrobial therapy
	*Antibiotics if severe illness:		*Antibiotics if severe illness:
	**[[Macrolides]]		**[[Macrolides]] (e.g. [[Azithromycin]])
	~~***~~[[Azithromycin]]		**[[Fluroquinolones]] (e.g. [[Ciprofloxacin]])
	**[[Fluroquinolones]]		**Note - resistance is becoming prevalent (up to 25% resistance with [[ciprofloxacin]]<ref>CDC. Campylobacter (Campylobacteriosis) - Antibiotic resistance. Last modified October 2, 2017. https://www.cdc.gov/campylobacter/campy-antibiotic-resistance.html</ref>)
	~~***~~[[Ciprofloxacin]]
	*Note - resistance is becoming prevalent
	**Especially [[ciprofloxacin]]~~, which is as high as 25% resistance now~~<ref>CDC. Campylobacter (Campylobacteriosis) - Antibiotic resistance. Last modified October 2, 2017. https://www.cdc.gov/campylobacter/campy-antibiotic-resistance.html</ref>

	==Disposition==		==Disposition==
	*~~Home for most~~ patients		*Most patients can be discharged
	*Admit for rehydration in those with severe illness/inability to tolerate PO		*Admit for rehydration in those with severe illness/inability to tolerate PO

Línea 66:		Línea 64:

	==External Links==		==External Links==


	==References==		==References==

Kxl328: /* Managementhttp://www.cdc.gov/nczved/divisions/dfbmd/diseases/campylobacter/#treat */

2018-09-24T21:46:44Z

Managementhttp://www.cdc.gov/nczved/divisions/dfbmd/diseases/campylobacter/#treat

← Revisión anterior		Revisión del 21:46 24 sep 2018
Línea 55:		Línea 55:
	**[[Fluroquinolones]]		**[[Fluroquinolones]]
	***[[Ciprofloxacin]]		***[[Ciprofloxacin]]
	*Note - resistance is becoming prevalent~~, especially~~ ciprofloxacin, which is as high as 25% now<ref>CDC. Campylobacter (Campylobacteriosis) - Antibiotic resistance. Last modified October 2, 2017. https://www.cdc.gov/campylobacter/campy-antibiotic-resistance.html</ref>		*Note - resistance is becoming prevalent
			**Especially [[ciprofloxacin]], which is as high as 25% resistance now<ref>CDC. Campylobacter (Campylobacteriosis) - Antibiotic resistance. Last modified October 2, 2017. https://www.cdc.gov/campylobacter/campy-antibiotic-resistance.html</ref>

	==Disposition==		==Disposition==

Kxl328: /* Managementhttp://www.cdc.gov/nczved/divisions/dfbmd/diseases/campylobacter/#treat */

2018-09-24T21:46:04Z

Managementhttp://www.cdc.gov/nczved/divisions/dfbmd/diseases/campylobacter/#treat

← Revisión anterior		Revisión del 21:46 24 sep 2018
Línea 55:		Línea 55:
	**[[Fluroquinolones]]		**[[Fluroquinolones]]
	***[[Ciprofloxacin]]		***[[Ciprofloxacin]]
	*Note- resistance is becoming prevalent		*Note - resistance is becoming prevalent, especially ciprofloxacin, which is as high as 25% now<ref>CDC. Campylobacter (Campylobacteriosis) - Antibiotic resistance. Last modified October 2, 2017. https://www.cdc.gov/campylobacter/campy-antibiotic-resistance.html</ref>

	==Disposition==		==Disposition==

Josgood: /* Background */

2017-04-23T06:15:27Z

Background

← Revisión anterior		Revisión del 06:15 23 abr 2017
Línea 3:		Línea 3:
	*Commonly found in animal feces		*Commonly found in animal feces
	*Caused by oral-fecal transmission		*Caused by oral-fecal transmission
	*Associated with [[Guillain-Barre syndrome]] and Reiter syndrome		*Associated with [[Guillain-Barre syndrome]] and [[Reactive arthritis\|Reiter syndrome]]

	==Clinical Features==		==Clinical Features==

Neil.m.young: Text replacement - "==Diagnostic Evaluation==" to "==Evaluation=="

2016-07-28T05:18:55Z

Text replacement - "==Diagnostic Evaluation==" to "==Evaluation=="

← Revisión anterior		Revisión del 05:18 28 jul 2016
Línea 33:		Línea 33:
	{{Diarrhea DDX}}		{{Diarrhea DDX}}

	==~~Diagnostic~~ Evaluation==		==Evaluation==
	*Initiate work up in patients:		*Initiate work up in patients:
	**Appearing toxic		**Appearing toxic

Neil.m.young: Text replacement - "* " to "*"

2016-07-06T07:31:31Z

Text replacement - "* " to "*"

← Revisión anterior		Revisión del 07:31 6 jul 2016
Línea 1:		Línea 1:
	==Background==		==Background==
	* [[Gram negative]], non spore forming bacteria		*[[Gram negative]], non spore forming bacteria
	* Commonly found in animal feces		*Commonly found in animal feces
	* Caused by oral-fecal transmission		*Caused by oral-fecal transmission
	* Associated with [[Guillain-Barre syndrome]] and Reiter syndrome		*Associated with [[Guillain-Barre syndrome]] and Reiter syndrome

	==Clinical Features==		==Clinical Features==
	* Acute diarrheal illness (<3 weeks)		*Acute diarrheal illness (<3 weeks)
	* Severe [[abdominal pain]]		*Severe [[abdominal pain]]
	* [[Fever]]		*[[Fever]]
	* Bloody/voluminous/purulent stools		*Bloody/voluminous/purulent stools
	* Systemic illness/symptoms		*Systemic illness/symptoms

	==Differential Diagnosis==		==Differential Diagnosis==
	* Infectious:		*Infectious:
	** [[Salmonella]]		**[[Salmonella]]
	** [[Shigella]]		**[[Shigella]]
	** Shiga toxin-producing [[E. coli]]		**Shiga toxin-producing [[E. coli]]
	** [[E. coli]] 0157:H7		**[[E. coli]] 0157:H7
	** [[Entamoeba histolytica]]		**[[Entamoeba histolytica]]
	** [[Yersinia]]		**[[Yersinia]]
	** [[Vibrio]]		**[[Vibrio]]
	** [[C. difficile ]]		**[[C. difficile ]]
	* Non-infectious:		*Non-infectious:
	** [[Inflammatory bowel disease]]		**[[Inflammatory bowel disease]]
	** [[GI bleed]]		**[[GI bleed]]
	** [[Adrenal insufficiency]]		**[[Adrenal insufficiency]]
	** [[Mesenteric ischemia]]		**[[Mesenteric ischemia]]
	** [[Thyroid storm]]		**[[Thyroid storm]]
	** [[Toxicologic exposure]]		**[[Toxicologic exposure]]
	** [[Radiation syndrome]]		**[[Radiation syndrome]]

	{{Diarrhea DDX}}		{{Diarrhea DDX}}

	==Diagnostic Evaluation==		==Diagnostic Evaluation==
	* Initiate work up in patients:		*Initiate work up in patients:
	** Appearing toxic		**Appearing toxic
	** Febrile		**Febrile
	** Diarrheal illness lasting >3 days		**Diarrheal illness lasting >3 days
	** Blood or pus in stool		**Blood or pus in stool
	** Immunocompromised patients with presumed infectious diarrhea		**Immunocompromised patients with presumed infectious diarrhea
	* Bacterial stool culture		*Bacterial stool culture
	* Stool ova and parasites if concern for parasitic infection		*Stool ova and parasites if concern for parasitic infection
	* Consider [[C. difficile]] PCR if patient has risk factors		*Consider [[C. difficile]] PCR if patient has risk factors
	* Note- in many labs, stool culture tests for [[Salmonella]], [[Shigella]], and [[Campylobacter]]; discuss with your lab for further testing		*Note- in many labs, stool culture tests for [[Salmonella]], [[Shigella]], and [[Campylobacter]]; discuss with your lab for further testing
	* Note- not every patient with fever and diarrhea needs work up, use clinical judgment		*Note- not every patient with fever and diarrhea needs work up, use clinical judgment

	==Management<ref>http://www.cdc.gov/nczved/divisions/dfbmd/diseases/campylobacter/#treat</ref>==		==Management<ref>http://www.cdc.gov/nczved/divisions/dfbmd/diseases/campylobacter/#treat</ref>==
	* Fluid resuscitation- oral rehydration therapy preferred		*Fluid resuscitation- oral rehydration therapy preferred
	* Avoid antimotility agents with bloody diarrhea		*Avoid antimotility agents with bloody diarrhea
	* Many recover without antimicrobial therapy		*Many recover without antimicrobial therapy
	* Antibiotics if severe illness:		*Antibiotics if severe illness:
	** [[Macrolides]]		**[[Macrolides]]
	*** [[Azithromycin]]		***[[Azithromycin]]
	** [[Fluroquinolones]]		**[[Fluroquinolones]]
	*** [[Ciprofloxacin]]		***[[Ciprofloxacin]]
	* Note- resistance is becoming prevalent		*Note- resistance is becoming prevalent

	==Disposition==		==Disposition==
	* Home for most patients		*Home for most patients
	* Admit for rehydration in those with severe illness/inability to tolerate PO		*Admit for rehydration in those with severe illness/inability to tolerate PO

	==See Also==		==See Also==

Rossdonaldson1 at 11:23, 17 November 2015

2015-11-17T11:23:12Z

← Revisión anterior		Revisión del 11:23 17 nov 2015
Línea 11:		Línea 11:
	* Bloody/voluminous/purulent stools		* Bloody/voluminous/purulent stools
	* Systemic illness/symptoms		* Systemic illness/symptoms


	==Differential Diagnosis==		==Differential Diagnosis==
Línea 43:		Línea 42:
	* Bacterial stool culture		* Bacterial stool culture
	* Stool ova and parasites if concern for parasitic infection		* Stool ova and parasites if concern for parasitic infection
	* Consider C. difficile PCR if patient has risk factors		* Consider [[C. difficile]] PCR if patient has risk factors
	* Note- in many labs, stool culture tests for Salmonella, Shigella, and Campylobacter; discuss with your lab for further testing		* Note- in many labs, stool culture tests for [[Salmonella]], [[Shigella]], and [[Campylobacter]]; discuss with your lab for further testing
	* Note- not every patient with fever and diarrhea needs work up, use clinical judgment		* Note- not every patient with fever and diarrhea needs work up, use clinical judgment


	==Management<ref>http://www.cdc.gov/nczved/divisions/dfbmd/diseases/campylobacter/#treat</ref>==		==Management<ref>http://www.cdc.gov/nczved/divisions/dfbmd/diseases/campylobacter/#treat</ref>==
Línea 62:		Línea 60:
	* Home for most patients		* Home for most patients
	* Admit for rehydration in those with severe illness/inability to tolerate PO		* Admit for rehydration in those with severe illness/inability to tolerate PO

	==See Also==		==See Also==
	*[[Diarrhea]]		*[[Diarrhea]]
Línea 69:		Línea 68:
	==References==		==References==
	<references/>		<references/>
	* Kman N. Disorders Presenting Primarily with Diarrhea. In: ''Tintinalli's Emergency Medicine''. 7th ed. McGraw-Hill. 2011: 531-536.

	[[Category:ID]]		[[Category:ID]]

Rossdonaldson1: /* Differential Diagnosis */

2015-09-16T15:40:50Z

Differential Diagnosis

← Revisión anterior		Revisión del 15:40 16 sep 2015
Línea 32:		Línea 32:
	** [[Radiation syndrome]]		** [[Radiation syndrome]]

			{{Diarrhea DDX}}

	==Diagnostic Evaluation==		==Diagnostic Evaluation==

Rossdonaldson1: /* See Also */

2015-09-16T15:40:20Z

← Revisión anterior		Revisión del 15:40 16 sep 2015
Línea 63:		Línea 63:
	* Admit for rehydration in those with severe illness/inability to tolerate PO		* Admit for rehydration in those with severe illness/inability to tolerate PO
	==See Also==		==See Also==
	[[Diarrhea]]		*[[Diarrhea]]

	==External Links==		==External Links==