Aspirin - Revision history

Danbot: Switch SMW query from broadtable to table format for better layout with TOC

2026-03-20T21:55:52Z

Switch SMW query from broadtable to table format for better layout with TOC

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Danbot: Fix SMW query: replace link=subject with mainlabel=- to fix broken subobject fragment links

2026-03-20T17:25:04Z

Fix SMW query: replace link=subject with mainlabel=- to fix broken subobject fragment links

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Danbot: Add dynamic SMW Indications by Condition table (auto-populated from disease pages via MedicationDose template)

2026-03-20T16:43:11Z

Add dynamic SMW Indications by Condition table (auto-populated from disease pages via MedicationDose template)

@@ Línea 48: / Línea 48: @@
 *Excretion: Renal, dialyzable
 *Mechanism of Action: Irreversible cyclooxygenase inhibitor, thus preventing prostaglandin synthesis and platelet activation
 ==See Also==

Elcatracho: /* See Also */

2021-03-06T03:06:13Z

Humanguy: /* General */ added dosage forms

2017-10-11T20:23:37Z

General: added dosage forms

← Revisión anterior		Revisión del 20:23 11 oct 2017
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	==General==		==General==
	*Type: [[Antiplatelet]], [[NSAID]]		*Type: [[Antiplatelet]], [[NSAID]]
	*Dosage Forms:		*Dosage Forms: tablet, delayed-release tablet, chewable tablet, enteric-coated tablet, oral chewing gum, extended release capsule
	*Common Trade Names: Aspirin, Baby Aspirin, ASA		*Common Trade Names: Aspirin, Baby Aspirin, ASA
	*Usage: Analgesic, antipyretic, antiplatelet		*Usage: Analgesic, antipyretic, antiplatelet

ClaireLewis at 15:39, 22 August 2017

2017-08-22T15:39:28Z

← Revisión anterior		Revisión del 15:39 22 ago 2017
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	==General==		==General==
	*Type: [[Antiplatelet]]		*Type: [[Antiplatelet]], [[NSAID]]
	*Dosage Forms:		*Dosage Forms:
	*Common Trade Names: Aspirin, Baby Aspirin, ASA		*Common Trade Names: Aspirin, Baby Aspirin, ASA
	*Usage:		*Usage: Analgesic, antipyretic, antiplatelet
	**Pain reliever/fever reducer
	**Antiplatelet

	==Adult Dosing==		==Adult Dosing==
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	==Pediatric Dosing==		==Pediatric Dosing==
	*2 ~~to 11 years~~: 10 to ~~15mg~~/kg ~~orally~~ or ~~rectally every 4 to 6 hours as needed~~, ~~not~~ to ~~exceed 4 g~~/day.		'''''Avoid use''' in children, especially those with viral syndrome, due to risk of [[Reye syndrome]]''
	*~~12 years or older~~: ~~325 to 650mg orally or rectally every 4 hours as needed, not to exceed 4 g~~/day		*Fever, pain
			**>12yo: 325 to 650mg PO or PR q4-6h
			*2-11yo: 10 to 15 mg/kg PO or PR q4-6h
			*Kawasaki: 80-100 mg/kg/day (divided q4-6h) PO until afebrile 48-72h or day 14, then 3-5mg/kg/day until no evidence of coronary changes
			*Stroke: 1 to 5 mg/kg/day PO
			*Juvenile RA: 90-130 mg/kg/day PO divided q4-6h

	==Special Populations==		==Special Populations==
	*[[Drug Ratings in Pregnancy\|Pregnancy Rating]]: D		*[[Drug Ratings in Pregnancy\|Pregnancy Rating]]: C (1st-2nd trimester), D (3rd trimester)
	*Lactation: ~~best avoided, low dose may~~ be ~~considered for antiplatelet~~		*Lactation: Infant risk cannot be ruled out
	*Renal Dosing		*Renal Dosing: if CrCl <10, avoid use
	**Adult: if CrCl <10, avoid use		*Hepatic Dosing: avoid if severe impairment
	**Pediatric: if CrCl <10, avoid use
	*Hepatic Dosing
	**Adult: ~~not defined~~
	**Pediatric: not defined

	==Contraindications==		==Contraindications==
	*Allergy to class/drug		*Allergy to class/drug
	**[[Hives]], ~~[[Facial swelling]]~~, ~~[[Asthma]], [[Shock]]~~		* Syndrome of asthma, rhinitis, and nasal polyps
	*Bleeding, Ulcers, Asthma

	==Adverse Reactions==		==Adverse Reactions==
	===Serious===		===Serious===
	*[[Aspirin (Salicylate) Toxicity]]		*See [[Aspirin (Salicylate) Toxicity]]
	*[[Reye syndrome]] - Children and teenagers should not use this medicine for chicken pox or ~~flu~~ symptoms		*[[Reye syndrome]] - Children and teenagers should not use this medicine for chicken pox or viral symptoms
			*GI ulcer
			*Hemorrhage
			*Exudative age-related macular degeneration
			*Bronchospasm
			*Tinnitus
			*Angioedema
	===Common===		===Common===


	==Pharmacology==		==Pharmacology==
	*Half-life:		*Half-life: 20-60m, Salicylic acid: 6h
	*Metabolism:		*Metabolism: Hepatic
	*Excretion:		*Excretion: Renal, dialyzable
	*Mechanism of Action:		*Mechanism of Action: Irreversible cyclooxygenase inhibitor, thus preventing prostaglandin synthesis and platelet activation

	==See Also==		==See Also==

Neil.m.young: Text replacement - "0 mg" to "0mg"

2016-07-19T15:07:06Z

Text replacement - "0 mg" to "0mg"

← Revisión anterior		Revisión del 15:07 19 jul 2016
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	==Adult Dosing==		==Adult Dosing==
	*325 to ~~650 mg~~ orally or rectally every 4 hours as needed, not to exceed 4 g/day		*325 to 650mg orally or rectally every 4 hours as needed, not to exceed 4 g/day
	*324mg chewable for [[ACS]]		*324mg chewable for [[ACS]]
	*81mg (baby) Aspirin common daily cardiac risk reduction dose		*81mg (baby) Aspirin common daily cardiac risk reduction dose
Línea 14:		Línea 14:
	==Pediatric Dosing==		==Pediatric Dosing==
	*2 to 11 years: 10 to 15mg/kg orally or rectally every 4 to 6 hours as needed, not to exceed 4 g/day.		*2 to 11 years: 10 to 15mg/kg orally or rectally every 4 to 6 hours as needed, not to exceed 4 g/day.
	*12 years or older: 325 to ~~650 mg~~ orally or rectally every 4 hours as needed, not to exceed 4 g/day		*12 years or older: 325 to 650mg orally or rectally every 4 hours as needed, not to exceed 4 g/day

	==Special Populations==		==Special Populations==

Neil.m.young: Text replacement - "1 mg" to "1mg"

2016-07-19T12:08:16Z

Text replacement - "1 mg" to "1mg"

← Revisión anterior		Revisión del 12:08 19 jul 2016
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	*325 to 650 mg orally or rectally every 4 hours as needed, not to exceed 4 g/day		*325 to 650 mg orally or rectally every 4 hours as needed, not to exceed 4 g/day
	*324mg chewable for [[ACS]]		*324mg chewable for [[ACS]]
	*~~81 mg~~ (baby) Aspirin common daily cardiac risk reduction dose		*81mg (baby) Aspirin common daily cardiac risk reduction dose

	==Pediatric Dosing==		==Pediatric Dosing==

Neil.m.young: Text replacement - "4 mg" to "4mg"

2016-07-19T05:45:01Z

Text replacement - "4 mg" to "4mg"

← Revisión anterior		Revisión del 05:45 19 jul 2016
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	==Adult Dosing==		==Adult Dosing==
	*325 to 650 mg orally or rectally every 4 hours as needed, not to exceed 4 g/day		*325 to 650 mg orally or rectally every 4 hours as needed, not to exceed 4 g/day
	*~~324 mg~~ chewable for [[ACS]]		*324mg chewable for [[ACS]]
	*81 mg (baby) Aspirin common daily cardiac risk reduction dose		*81 mg (baby) Aspirin common daily cardiac risk reduction dose

Neil.m.young: Text replacement - "5 mg" to "5mg"

2016-07-19T01:33:44Z

Text replacement - "5 mg" to "5mg"

← Revisión anterior		Revisión del 01:33 19 jul 2016
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	==Pediatric Dosing==		==Pediatric Dosing==
	*2 to 11 years: 10 to ~~15 mg~~/kg orally or rectally every 4 to 6 hours as needed, not to exceed 4 g/day.		*2 to 11 years: 10 to 15mg/kg orally or rectally every 4 to 6 hours as needed, not to exceed 4 g/day.
	*12 years or older: 325 to 650 mg orally or rectally every 4 hours as needed, not to exceed 4 g/day		*12 years or older: 325 to 650 mg orally or rectally every 4 hours as needed, not to exceed 4 g/day

← Revisión anterior		Revisión del 03:06 6 mar 2021
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	==See Also==		==See Also==
	*[[Aspirin (Salicylate) Toxicity]]		*[[Aspirin (Salicylate) Toxicity]]
			*[[Antiplatelet medications]]
			*[[Antiplatelet agent reversal]]

	==References==		==References==