Antibiotic Basics - Revision history

Rossdonaldson1: Redirected page to Antibiotics (Main)

2014-02-10T23:48:42Z

← Revisión anterior		Revisión del 23:48 10 feb 2014
Línea 1:		Línea 1:
	~~==Beta-Lactams==~~		#REDIRECT[[Antibiotics (Main)]]
	*'''[[Penicillins]]'''
	** Strep Pharyngitis (including scarlet fever) Streptococcal Toxic Shock and Necrotizing Fascitis
	*** Penicillin ''plus'' clindamycin (to decrease toxin synthesis)
	** Meningococcus Meningitis
	** Syphilis (Primary, 2ndary, and latent syphilis < 1 year duration)
	** Actinomycosis
	** Anthrax
	** Clostridial infections
	** Listeria
	** Pasteurella
	* Penicilinase-Resistant Penicillins
	** Nafcillin, oxacillin, dicloxacillin
	*** Agents of 1st choice for treatment of S. aureus and S. epidermidis that are not methicillin-reistant
	*'''Expanded-Spectrum Penicillins'''
	** Ampicillin, amoxicillin (+ clavulanate)
	*** Upper Respiratory Infections (due to S. pyogenes, S. pneumoniae, H. influenzae)
	**** Sinusitis
	**** Otitis media
	**** Acute exacerbation of chronic bronchitis
	*** Listeria
	* Antipseudomonal Penicillins
	** Piperacillin
	*** Infection following burns
	*** Neutropenia
	*'''1st Gen [[Cephalosporins]]'''
	** Cefazolin, [[Cephalexin]]
	*** Skin and soft tissue infections (why is agent of choice before gen sx)
	** [[Ceftriaxone_Cross-reactivity\|Cross-reactivity of PCN]] allergy <10%
	*'''2nd Gen Cephalosporins'''
	** Cefuroxime
	*** Intestinal anaerobes (why is agent of chioce for colorectal sx)
	*** Largely displaced by 3rd gen agents
	*'''3rd Gen Cephalosporins'''
	** Ceftriaxone, Ceftazidime, Cefixime
	*** Drug of choice for serious infections due to:
	**** Klebsiella
	**** Enterobacter
	**** Proteus
	**** Haemophilus
	*** Gonorrhea
	*** Lyme disease
	*** Meningitis (+ vanc and ampicillin)
	*** Pseudomonas meningitis (+ AG)
	*'''4th Gen Cephalosporins'''
	** Cefepime
	*** Resistant, nosocomial infections
	* Carbapenems
	** Imipenem (+ cilastatin), meropenem
	*** Cephalosporin-resistant nosocomial bacteria
	*** Empirical treatment of serious infections in patients who recently received other b-lactams
	* Aztreonam
	** Antimicrobial activity more closely resembles AG's (only active against gram -)
	*** Enterobacter, pseudomonas, H. influenzae, gonococci
	*** Little allergic cross-reactivity with B-lactam antibiotics

	~~==[[Aminoglycosides]]==~~
	* Gentamicin, amikacin, streptomycin (either alone or with B-lactam)
	** Serious gram-negative bacillary infections
	*** Ill patient with pyelonephritis
	*** Meningitis (due to Pseudomonas, Acinetobacter)
	*** Peritoneal Dialysis–Associated Peritonitis
	*** Bacterial endocarditis?
	* Caution: Use in patients with Myasthenia Gravis, can precipitate crisis

	~~==[[Sulfonamides]]==~~
	* Trimethoprim-sulfamethoxazole
	** 1st line for uncomplicated lower UTI (especially chronic and recurrent infections)
	** PCP pneumonia
	** Acute exacerbations of chronic bronchitis
	** Maxillary sinusitis

	~~==[[Fluoroquinolones]]==~~
	* UTI (2nd line)
	* Prostatitis
	* Chlamydia
	* PID
	* Traveler's diarrhea

	~~==[[Tetracyclines]]==~~
	* Mycoplasma
	* Chlamydia
	* PID (combined with cephalosporin)
	* Epididymitis
	* Anthrax

	~~==[[Macrolides]]==~~
	* Erythromycin, Clarithromycin, Azithromycin
	** Community-acquired PNA
	** Mycoplasma
	** Legionnaires' Disease
	** Chlamydia (single dose)
	** H. Pylori
	** Traveler's diarrhea (children and pregnant women)

	~~==[[Clindamycin]]==~~
	* Drug of choice for lung abscess and anaerobic lung and pleural space infections
	* Toxin-mediated disease, i.e. toxic shock syndrome (TSS)

	~~{{Template:Clinically Utilized Antibiotics}}~~

	~~==See Also==~~
	*[[Antibiotics (Main)]]

	~~==Source==~~
	~~Goodman & Gilman's Pharmacology~~

	~~[[Category:ID]]~~
	~~[[Category:Drugs~~]]

Rossdonaldson1 at 23:46, 10 February 2014

2014-02-10T23:46:06Z

← Revisión anterior		Revisión del 23:46 10 feb 2014
Línea 97:		Línea 97:
	* Drug of choice for lung abscess and anaerobic lung and pleural space infections		* Drug of choice for lung abscess and anaerobic lung and pleural space infections
	* Toxin-mediated disease, i.e. toxic shock syndrome (TSS)		* Toxin-mediated disease, i.e. toxic shock syndrome (TSS)

			{{Template:Clinically Utilized Antibiotics}}

	==See Also==		==See Also==
Línea 103:		Línea 105:
	==Source==		==Source==
	Goodman & Gilman's Pharmacology		Goodman & Gilman's Pharmacology

	~~{{Template:Clinically Utilized Antibiotics}}~~

	[[Category:ID]]		[[Category:ID]]
	[[Category:Drugs]]		[[Category:Drugs]]

Rossdonaldson1 at 23:42, 10 February 2014

2014-02-10T23:42:10Z

← Revisión anterior		Revisión del 23:42 10 feb 2014
Línea 104:		Línea 104:
	Goodman & Gilman's Pharmacology		Goodman & Gilman's Pharmacology

	{{Template:~~Cell Wall~~ Antibiotics}}		{{Template:Clinically Utilized Antibiotics}}

	[[Category:ID]]		[[Category:ID]]
	[[Category:Drugs]]		[[Category:Drugs]]

Rossdonaldson1 at 23:37, 10 February 2014

2014-02-10T23:37:18Z

← Revisión anterior		Revisión del 23:37 10 feb 2014
Línea 1:		Línea 1:
	==Beta-Lactams==		==Beta-Lactams==
	*'''~~Penicillin~~'''		*'''[[Penicillins]]'''
	** Strep Pharyngitis (including scarlet fever) Streptococcal Toxic Shock and Necrotizing Fascitis		** Strep Pharyngitis (including scarlet fever) Streptococcal Toxic Shock and Necrotizing Fascitis
	*** Penicillin ''plus'' clindamycin (to decrease toxin synthesis)		*** Penicillin ''plus'' clindamycin (to decrease toxin synthesis)
Línea 55:		Línea 55:
	*** Little allergic cross-reactivity with B-lactam antibiotics		*** Little allergic cross-reactivity with B-lactam antibiotics

	==Aminoglycosides==		==[[Aminoglycosides]]==
	* Gentamicin, amikacin, streptomycin (either alone or with B-lactam)		* Gentamicin, amikacin, streptomycin (either alone or with B-lactam)
	** Serious gram-negative bacillary infections		** Serious gram-negative bacillary infections
Línea 64:		Línea 64:
	* Caution: Use in patients with Myasthenia Gravis, can precipitate crisis		* Caution: Use in patients with Myasthenia Gravis, can precipitate crisis

	==Sulfonamides==		==[[Sulfonamides]]==
	* Trimethoprim-sulfamethoxazole		* Trimethoprim-sulfamethoxazole
	** 1st line for uncomplicated lower UTI (especially chronic and recurrent infections)		** 1st line for uncomplicated lower UTI (especially chronic and recurrent infections)
Línea 71:		Línea 71:
	** Maxillary sinusitis		** Maxillary sinusitis

	==Fluoroquinolones==		==[[Fluoroquinolones]]==
	* UTI (2nd line)		* UTI (2nd line)
	* Prostatitis		* Prostatitis
Línea 78:		Línea 78:
	* Traveler's diarrhea		* Traveler's diarrhea

	==Tetracyclines==		==[[Tetracyclines]]==
	* Mycoplasma		* Mycoplasma
	* Chlamydia		* Chlamydia
Línea 85:		Línea 85:
	* Anthrax		* Anthrax

	==Macrolides==		==[[Macrolides]]==
	* Erythromycin, Clarithromycin, Azithromycin		* Erythromycin, Clarithromycin, Azithromycin
	** Community-acquired PNA		** Community-acquired PNA
Línea 94:		Línea 94:
	** Traveler's diarrhea (children and pregnant women)		** Traveler's diarrhea (children and pregnant women)

	==Clindamycin==		==[[Clindamycin]]==
	* Drug of choice for lung abscess and anaerobic lung and pleural space infections		* Drug of choice for lung abscess and anaerobic lung and pleural space infections
	* Toxin-mediated disease, i.e. toxic shock syndrome (TSS)		* Toxin-mediated disease, i.e. toxic shock syndrome (TSS)

Rossdonaldson1 at 21:04, 10 February 2014

2014-02-10T21:04:58Z

← Revisión anterior		Revisión del 21:04 10 feb 2014
Línea 103:		Línea 103:
	==Source==		==Source==
	Goodman & Gilman's Pharmacology		Goodman & Gilman's Pharmacology

			{{Template:Cell Wall Antibiotics}}

	[[Category:ID]]		[[Category:ID]]
	[[Category:Drugs]]		[[Category:Drugs]]

Rossdonaldson1: /* Beta-Lactams */

2014-02-10T20:42:15Z

Beta-Lactams

← Revisión anterior		Revisión del 20:42 10 feb 2014
Línea 24:		Línea 24:
	*** Infection following burns		*** Infection following burns
	*** Neutropenia		*** Neutropenia
	*'''1st Gen Cephalosporins'''		*'''1st Gen [[Cephalosporins]]'''
	** Cefazolin, [[Cephalexin]]		** Cefazolin, [[Cephalexin]]
	*** Skin and soft tissue infections (why is agent of choice before gen sx)		*** Skin and soft tissue infections (why is agent of choice before gen sx)

Rossdonaldson1: /* Beta-Lactams */

2014-02-05T07:31:45Z

Beta-Lactams

← Revisión anterior		Revisión del 07:31 5 feb 2014
Línea 25:		Línea 25:
	*** Neutropenia		*** Neutropenia
	*'''1st Gen Cephalosporins'''		*'''1st Gen Cephalosporins'''
	** Cefazolin, ~~cephalexin~~		** Cefazolin, [[Cephalexin]]
	*** Skin and soft tissue infections (why is agent of choice before gen sx)		*** Skin and soft tissue infections (why is agent of choice before gen sx)
	** [[Ceftriaxone_Cross-reactivity\|Cross-reactivity of PCN]] allergy <10%		** [[Ceftriaxone_Cross-reactivity\|Cross-reactivity of PCN]] allergy <10%

Rossdonaldson1: /* Beta-Lactams */

2014-02-05T06:43:54Z

Beta-Lactams

← Revisión anterior		Revisión del 06:43 5 feb 2014
Línea 1:		Línea 1:
	==Beta-Lactams==		==Beta-Lactams==
	'''* Penicillin'''		*'''Penicillin'''
	** Strep Pharyngitis (including scarlet fever) Streptococcal Toxic Shock and Necrotizing Fascitis		** Strep Pharyngitis (including scarlet fever) Streptococcal Toxic Shock and Necrotizing Fascitis
	*** Penicillin ''plus'' clindamycin (to decrease toxin synthesis)		*** Penicillin ''plus'' clindamycin (to decrease toxin synthesis)
Línea 13:		Línea 13:
	** Nafcillin, oxacillin, dicloxacillin		** Nafcillin, oxacillin, dicloxacillin
	*** Agents of 1st choice for treatment of S. aureus and S. epidermidis that are not methicillin-reistant		*** Agents of 1st choice for treatment of S. aureus and S. epidermidis that are not methicillin-reistant
	'''* Expanded-Spectrum Penicillins'''		*'''Expanded-Spectrum Penicillins'''
	** Ampicillin, amoxicillin (+ clavulanate)		** Ampicillin, amoxicillin (+ clavulanate)
	*** Upper Respiratory Infections (due to S. pyogenes, S. pneumoniae, H. influenzae)		*** Upper Respiratory Infections (due to S. pyogenes, S. pneumoniae, H. influenzae)
Línea 24:		Línea 24:
	*** Infection following burns		*** Infection following burns
	*** Neutropenia		*** Neutropenia
	'''* 1st Gen Cephalosporins'''		*'''1st Gen Cephalosporins'''
	** Cefazolin, cephalexin		** Cefazolin, cephalexin
	*** Skin and soft tissue infections (why is agent of choice before gen sx)		*** Skin and soft tissue infections (why is agent of choice before gen sx)
	** [[Ceftriaxone_Cross-reactivity\|Cross-reactivity of PCN]] allergy <10%		** [[Ceftriaxone_Cross-reactivity\|Cross-reactivity of PCN]] allergy <10%
	'''* 2nd Gen Cephalosporins'''		*'''2nd Gen Cephalosporins'''
	** Cefuroxime		** Cefuroxime
	*** Intestinal anaerobes (why is agent of chioce for colorectal sx)		*** Intestinal anaerobes (why is agent of chioce for colorectal sx)
	*** Largely displaced by 3rd gen agents		*** Largely displaced by 3rd gen agents
	* '''3rd Gen Cephalosporins'''		*'''3rd Gen Cephalosporins'''
	** Ceftriaxone, Ceftazidime, Cefixime		** Ceftriaxone, Ceftazidime, Cefixime
	*** Drug of choice for serious infections due to:		*** Drug of choice for serious infections due to:
Línea 43:		Línea 43:
	*** Meningitis (+ vanc and ampicillin)		*** Meningitis (+ vanc and ampicillin)
	*** Pseudomonas meningitis (+ AG)		*** Pseudomonas meningitis (+ AG)
	* '''4th Gen Cephalosporins'''		*'''4th Gen Cephalosporins'''
	** Cefepime		** Cefepime
	*** Resistant, nosocomial infections		*** Resistant, nosocomial infections

Ostermayer: /* Beta-Lactams */

2013-10-05T17:54:07Z

Beta-Lactams

← Revisión anterior		Revisión del 17:54 5 oct 2013
Línea 1:		Línea 1:
	==Beta-Lactams==		==Beta-Lactams==
	* Penicillin		'''* Penicillin'''
	** Strep Pharyngitis (including scarlet fever) Streptococcal Toxic Shock and Necrotizing Fascitis		** Strep Pharyngitis (including scarlet fever) Streptococcal Toxic Shock and Necrotizing Fascitis
	*** Penicillin ''plus'' clindamycin (to decrease toxin synthesis)		*** Penicillin ''plus'' clindamycin (to decrease toxin synthesis)
Línea 13:		Línea 13:
	** Nafcillin, oxacillin, dicloxacillin		** Nafcillin, oxacillin, dicloxacillin
	*** Agents of 1st choice for treatment of S. aureus and S. epidermidis that are not methicillin-reistant		*** Agents of 1st choice for treatment of S. aureus and S. epidermidis that are not methicillin-reistant
	* Expanded-Spectrum Penicillins		'''* Expanded-Spectrum Penicillins'''
	** Ampicillin, amoxicillin (+ clavulanate)		** Ampicillin, amoxicillin (+ clavulanate)
	*** Upper Respiratory Infections (due to S. pyogenes, S. pneumoniae, H. influenzae)		*** Upper Respiratory Infections (due to S. pyogenes, S. pneumoniae, H. influenzae)
Línea 24:		Línea 24:
	*** Infection following burns		*** Infection following burns
	*** Neutropenia		*** Neutropenia
	* 1st Gen Cephalosporins		'''* 1st Gen Cephalosporins'''
	** Cefazolin, cephalexin		** Cefazolin, cephalexin
	*** Skin and soft tissue infections (why is agent of choice before gen sx)		*** Skin and soft tissue infections (why is agent of choice before gen sx)
	** [[Ceftriaxone_Cross-reactivity\|Cross-reactivity of PCN]] allergy <10%		** [[Ceftriaxone_Cross-reactivity\|Cross-reactivity of PCN]] allergy <10%
	* 2nd Gen Cephalosporins		'''* 2nd Gen Cephalosporins'''
	** Cefuroxime		** Cefuroxime
	*** Intestinal anaerobes (why is agent of chioce for colorectal sx)		*** Intestinal anaerobes (why is agent of chioce for colorectal sx)
	*** Largely displaced by 3rd gen agents		*** Largely displaced by 3rd gen agents
	* 3rd Gen Cephalosporins		* '''3rd Gen Cephalosporins'''
	** Ceftriaxone, Ceftazidime, Cefixime		** Ceftriaxone, Ceftazidime, Cefixime
	*** Drug of choice for serious infections due to:		*** Drug of choice for serious infections due to:
Línea 43:		Línea 43:
	*** Meningitis (+ vanc and ampicillin)		*** Meningitis (+ vanc and ampicillin)
	*** Pseudomonas meningitis (+ AG)		*** Pseudomonas meningitis (+ AG)
	* 4th Gen Cephalosporins		* '''4th Gen Cephalosporins'''
	** Cefepime		** Cefepime
	*** Resistant, nosocomial infections		*** Resistant, nosocomial infections

Ostermayer: /* Beta-Lactams */

2013-10-05T17:53:09Z

Beta-Lactams

← Revisión anterior		Revisión del 17:53 5 oct 2013
Línea 27:		Línea 27:
	** Cefazolin, cephalexin		** Cefazolin, cephalexin
	*** Skin and soft tissue infections (why is agent of choice before gen sx)		*** Skin and soft tissue infections (why is agent of choice before gen sx)
	** Cross-reactivity of PCN allergy ~~7% to 18~~%		** [[Ceftriaxone_Cross-reactivity\|Cross-reactivity of PCN]] allergy <10%
	* 2nd Gen Cephalosporins		* 2nd Gen Cephalosporins
	** Cefuroxime		** Cefuroxime