Anthrax - Revision history

Rossdonaldson1: /* Clinical Features */

2022-09-21T18:20:53Z

Clinical Features

← Revisión anterior		Revisión del 18:20 21 sep 2022
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	[[File:Anthrax PHIL 2033.png\|thumb\|A skin lesion with black eschar characteristic of anthrax]]		[[File:Anthrax PHIL 2033.png\|thumb\|A skin lesion with black eschar characteristic of anthrax]]
	[[File:PMC3493280 1756-0500-5-464-1.png\|thumb\|Cutaneous anthrax with associated marked edema.]]		[[File:PMC3493280 1756-0500-5-464-1.png\|thumb\|Cutaneous anthrax with associated marked edema.]]
			[[File:PMC3291463 05-1407-F.png\|thumb\|Initial skin lesion with black eschar and red border. By the time the picture was taken, the massive associated edema of hand and arm had subsided.]]
	===Inhalational (5%)===		===Inhalational (5%)===
	*Biphasic course		*Biphasic course

Rossdonaldson1: /* Clinical Features */

2022-09-21T18:18:33Z

Clinical Features

← Revisión anterior		Revisión del 18:18 21 sep 2022
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	[[File:Cutaneous_anthrax.png\|thumb\|Cutaneous anthrax]]		[[File:Cutaneous_anthrax.png\|thumb\|Cutaneous anthrax]]
	[[File:Anthrax PHIL 2033.png\|thumb\|A skin lesion with black eschar characteristic of anthrax]]		[[File:Anthrax PHIL 2033.png\|thumb\|A skin lesion with black eschar characteristic of anthrax]]
			[[File:PMC3493280 1756-0500-5-464-1.png\|thumb\|Cutaneous anthrax with associated marked edema.]]
	===Inhalational (5%)===		===Inhalational (5%)===
	*Biphasic course		*Biphasic course

Rossdonaldson1: /* Clinical Features */

2022-09-21T18:13:22Z

Clinical Features

← Revisión anterior		Revisión del 18:13 21 sep 2022
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	==Clinical Features==		==Clinical Features==
	[[File:Cutaneous anthrax lesion on the neck. PHIL 1934 lores.jpg\|thumb\|Cutaneous anthrax lesion on neck.]]		[[File:Cutaneous anthrax lesion on the neck. PHIL 1934 lores.jpg\|thumb\|Cutaneous anthrax lesion on neck.]]
			[[File:Cutaneous_anthrax.png\|thumb\|Cutaneous anthrax]]
			[[File:Anthrax PHIL 2033.png\|thumb\|A skin lesion with black eschar characteristic of anthrax]]
	===Inhalational (5%)===		===Inhalational (5%)===
	*Biphasic course		*Biphasic course
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	===Cutaneous (95%)===		===Cutaneous (95%)===
	~~[[File:Cutaneous_anthrax.png\|thumb\|Cutaneous anthrax]]~~
	*The disease will start as an area of erythema and edema and progress to a vesicle which ruptures forming a central black eschar which eventually falls off		*The disease will start as an area of erythema and edema and progress to a vesicle which ruptures forming a central black eschar which eventually falls off
	*Total course of lesion evolution occurs over 1 week		*Total course of lesion evolution occurs over 1 week

Ostermayer at 17:55, 18 September 2022

2022-09-18T17:55:45Z

← Revisión anterior		Revisión del 17:55 18 sep 2022
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	==Background==		==Background==
	*Gram positive ~~rod1~~, Bacillus anthracis, which is capable of surviving inhospitable conditions through the formation of endospores		*Gram positive rod, Bacillus anthracis, which is capable of surviving inhospitable conditions through the formation of endospores
	*Incubation period is 10 days with no ability for human to human transmission and therefore, no need for respiratory isolation		*Incubation period is 10 days with no ability for human to human transmission and therefore, no need for respiratory isolation
	**Though human to human transmission does not occur, potential harbors of spores (patient clothes) need to be isolated and decontaminated with 10% bleach<ref>Heninger SJ et al. Decontamination of Bacillus anthracis Spores: Evaluation of Various Disinfectants. Appl Biosaf. 2009 Jan 1; 14(1): 7–10.</ref>		**Though human to human transmission does not occur, potential harbors of spores (patient clothes) need to be isolated and decontaminated with 10% bleach<ref>Heninger SJ et al. Decontamination of Bacillus anthracis Spores: Evaluation of Various Disinfectants. Appl Biosaf. 2009 Jan 1; 14(1): 7–10.</ref>

Ostermayer at 17:50, 18 September 2022

2022-09-18T17:50:43Z

← Revisión anterior		Revisión del 17:50 18 sep 2022
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	==Background==		==Background==
	*Gram positive ~~rod~~, Bacillus anthracis, which is capable of surviving inhospitable conditions through the formation of endospores		*Gram positive rod1, Bacillus anthracis, which is capable of surviving inhospitable conditions through the formation of endospores
	*Incubation period is 10 days with no ability for human to human transmission and therefore, no need for respiratory isolation		*Incubation period is 10 days with no ability for human to human transmission and therefore, no need for respiratory isolation
	**Though human to human transmission does not occur, potential harbors of spores (patient clothes) need to be isolated and decontaminated with 10% bleach<ref>Heninger SJ et al. Decontamination of Bacillus anthracis Spores: Evaluation of Various Disinfectants. Appl Biosaf. 2009 Jan 1; 14(1): 7–10.</ref>		**Though human to human transmission does not occur, potential harbors of spores (patient clothes) need to be isolated and decontaminated with 10% bleach<ref>Heninger SJ et al. Decontamination of Bacillus anthracis Spores: Evaluation of Various Disinfectants. Appl Biosaf. 2009 Jan 1; 14(1): 7–10.</ref>

Rossdonaldson1: /* References */

2021-11-17T19:57:53Z

References

← Revisión anterior		Revisión del 19:57 17 nov 2021
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	[[Category:ID]]		[[Category:ID]]
	~~[[Category:Toxicology]]~~

Jonwarren: /* Gastrointestinal */

2021-03-14T18:13:13Z

Gastrointestinal

← Revisión anterior		Revisión del 18:13 14 mar 2021
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	===Gastrointestinal===		===Gastrointestinal===
	*Over the course of 7 days, nonspecific [[abdominal pain]], [[nausea and vomiting]] with progress to severe abdominal pain, [[hematemesis\|bloody emesis]] and [[diarrhea]] (usually bloody)<ref> CDC. Gastrointestinal anthrax after an animal-hide drumming event - New Hampshire and Massachusetts, 2009. MMWR Morb Mortal Wkly Rep. 2010 Jul 23;59(28):872-7. http://www.ncbi.nlm.nih.gov/pubmed/20651643</ref>		*Over the course of 7 days, nonspecific [[abdominal pain]], [[nausea and vomiting]] with progress to severe abdominal pain, [[hematemesis\|bloody emesis]] and [[diarrhea]] (usually bloody)<ref> CDC. Gastrointestinal anthrax after an animal-hide drumming event - New Hampshire and Massachusetts, 2009. MMWR Morb Mortal Wkly Rep. 2010 Jul 23;59(28):872-7. http://www.ncbi.nlm.nih.gov/pubmed/20651643</ref>
			*May present as oropharyngeal ulcers with [[dysphagia]]

	==Differential Diagnosis==		==Differential Diagnosis==

Rossdonaldson1 at 19:52, 12 January 2021

2021-01-12T19:52:01Z

← Revisión anterior		Revisión del 19:52 12 ene 2021
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	**Though human to human transmission does not occur, potential harbors of spores (patient clothes) need to be isolated and decontaminated with 10% bleach<ref>Heninger SJ et al. Decontamination of Bacillus anthracis Spores: Evaluation of Various Disinfectants. Appl Biosaf. 2009 Jan 1; 14(1): 7–10.</ref>		**Though human to human transmission does not occur, potential harbors of spores (patient clothes) need to be isolated and decontaminated with 10% bleach<ref>Heninger SJ et al. Decontamination of Bacillus anthracis Spores: Evaluation of Various Disinfectants. Appl Biosaf. 2009 Jan 1; 14(1): 7–10.</ref>
	*In general there is cutaneous, inhalational, and gastrointesinal anthrax.		*In general there is cutaneous, inhalational, and gastrointesinal anthrax.

			==Clinical Features==
			[[File:Cutaneous anthrax lesion on the neck. PHIL 1934 lores.jpg\|thumb\|Cutaneous anthrax lesion on neck.]]
	===Inhalational (5%)===		===Inhalational (5%)===
	*Biphasic course		*Biphasic course

	====Prodrome Period====		====Prodrome Period====
	*Early prodromal period often appears as an [[flu-like illness]]		*Early prodromal period often appears as an [[flu-like illness]]
	*[[Fever]], dry [[cough]], [[myalgia]], malaise		*[[Fever]], dry [[cough]], [[myalgia]], malaise
	*Transient clinical improvement followed by rapid decline		*Transient clinical improvement followed by rapid decline

	====Acute phase====		====Acute phase====
	*Severe [[respiratory distress]] with symptoms consisting of<ref>[http://emedicine.medscape.com/article/212127-overview Medscape: Anthrax]</ref>:		*Severe [[respiratory distress]] with symptoms consisting of<ref>[http://emedicine.medscape.com/article/212127-overview Medscape: Anthrax]</ref>:

Rossdonaldson1: /* Evaluation */

2021-01-12T19:49:17Z

Evaluation

← Revisión anterior		Revisión del 19:49 12 ene 2021
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	==Evaluation==		==Evaluation==
			[[File:Anthrax - inhalational.jpg\|thumb\|[[CXR]] of inhalational anthrax showing mediastinal widening.]]
	*[[CXR]]/CT		*[[CXR]]/CT
	**Widened mediastinum representing hemorrhagic mediastinitis		**Widened mediastinum representing hemorrhagic mediastinitis

Elcatracho: /* Background */

2020-12-15T19:04:59Z

Background

← Revisión anterior		Revisión del 19:04 15 dic 2020
Línea 1:		Línea 1:
	==Background==		==Background==
	*Gram positive rod, Bacillus anthracis, which is capable of surviving inhospitable ~~condition~~ through the formation of endospores~~. tough spores~~		*Gram positive rod, Bacillus anthracis, which is capable of surviving inhospitable conditions through the formation of endospores
	*Incubation period is 10 days with no ability for human to human transmission and therefore, no need for respiratory isolation		*Incubation period is 10 days with no ability for human to human transmission and therefore, no need for respiratory isolation
	**Though human to human transmission does not occur, potential harbors of spores (patient clothes) need to be isolated and decontaminated with 10% bleach<ref>Heninger SJ et al. Decontamination of Bacillus anthracis Spores: Evaluation of Various Disinfectants. Appl Biosaf. 2009 Jan 1; 14(1): 7–10.</ref>		**Though human to human transmission does not occur, potential harbors of spores (patient clothes) need to be isolated and decontaminated with 10% bleach<ref>Heninger SJ et al. Decontamination of Bacillus anthracis Spores: Evaluation of Various Disinfectants. Appl Biosaf. 2009 Jan 1; 14(1): 7–10.</ref>