Amebiasis - Revision history

Danbot: Add AntibioticDose template for Metronidazole colitis dosing; strip translate tags; fix drug links

2026-03-20T10:47:25Z

Add AntibioticDose template for Metronidazole colitis dosing; strip translate tags; fix drug links

Ostermayer: Marked this version for translation

2026-01-06T20:29:07Z

Marked this version for translation

← Revisión anterior		Revisión del 20:29 6 ene 2026
Línea 3:		Línea 3:


	==Background==		==Background== <!--T:1-->

			<!--T:2-->
	[[File:Amebiasis LifeCycle.gif\|thumb\|The life-cycle of various intestinal Entamoeba species.]]		[[File:Amebiasis LifeCycle.gif\|thumb\|The life-cycle of various intestinal Entamoeba species.]]
	*Fecal oral transmission of Entamoeba histolytica cyst		*Fecal oral transmission of Entamoeba histolytica cyst
Línea 15:		Línea 16:


	==Clinical Features==		==Clinical Features== <!--T:3-->

			<!--T:4-->
	*Asymptomatic vs. dysentery vs. extraintestinal abscesses		*Asymptomatic vs. dysentery vs. extraintestinal abscesses
	*Intestinal- several weeks of crampy [[Special:MyLanguage/abdominal pain\|abdominal pain]], weight loss, watery or bloody [[Special:MyLanguage/diarrhea\|diarrhea]]		*Intestinal- several weeks of crampy [[Special:MyLanguage/abdominal pain\|abdominal pain]], weight loss, watery or bloody [[Special:MyLanguage/diarrhea\|diarrhea]]
Línea 26:		Línea 28:


	==Differential Diagnosis==		==Differential Diagnosis== <!--T:5-->


	===Dysentery===		===Dysentery=== <!--T:6-->

			<!--T:7-->
	*Infectious- [[Special:MyLanguage/shigella\|shigella]], [[Special:MyLanguage/salmonella\|salmonella]], [[Special:MyLanguage/campylobacter\|campylobacter]], [[Special:MyLanguage/E. Coli\|E. Coli]].		*Infectious- [[Special:MyLanguage/shigella\|shigella]], [[Special:MyLanguage/salmonella\|salmonella]], [[Special:MyLanguage/campylobacter\|campylobacter]], [[Special:MyLanguage/E. Coli\|E. Coli]].
	*Noninfectious- [[Special:MyLanguage/Inflammatory bowel disease\|Inflammatory bowel disease]], [[Special:MyLanguage/ischemic colitis\|ischemic colitis]], [[Special:MyLanguage/diverticulitis\|diverticulitis]], AV malformation.		*Noninfectious- [[Special:MyLanguage/Inflammatory bowel disease\|Inflammatory bowel disease]], [[Special:MyLanguage/ischemic colitis\|ischemic colitis]], [[Special:MyLanguage/diverticulitis\|diverticulitis]], AV malformation.
Línea 48:		Línea 51:


	==Evaluation==		==Evaluation== <!--T:8-->


	===Labs===		===Labs=== <!--T:9-->

			<!--T:10-->
	*CBC		*CBC
	*Chem		*Chem
Línea 66:		Línea 70:


	===Imaging===		===Imaging=== <!--T:11-->

			<!--T:12-->
	*Abdominal Ultrasound		*Abdominal Ultrasound
	**58-98% SN for liver abscess (depending on size/location)		**58-98% SN for liver abscess (depending on size/location)
Línea 75:		Línea 80:


	==Management==		==Management== <!--T:13-->


	===Asymptomatic colonization===		===Asymptomatic colonization=== <!--T:14-->

			<!--T:15-->
	*[[Special:MyLanguage/Paromomycin\|Paromomycin]] or diloxanide		*[[Special:MyLanguage/Paromomycin\|Paromomycin]] or diloxanide



	===Colitis===		===Colitis=== <!--T:16-->

			<!--T:17-->
	*[[Special:MyLanguage/Metronidazole\|Metronidazole]]		*[[Special:MyLanguage/Metronidazole\|Metronidazole]]



	===Liver abscess===		===Liver abscess=== <!--T:18-->

			<!--T:19-->
	*[[Special:MyLanguage/Flagyl\|Flagyl]], [[Special:MyLanguage/tinidazole\|tinidazole]], [[Special:MyLanguage/paromomycin\|paromomycin]], or diloxanide		*[[Special:MyLanguage/Flagyl\|Flagyl]], [[Special:MyLanguage/tinidazole\|tinidazole]], [[Special:MyLanguage/paromomycin\|paromomycin]], or diloxanide
	*Consider drainage of abscess by IR if no response to antibiotics in 5 days, abscess > 5cm, or left lobe involvement		*Consider drainage of abscess by IR if no response to antibiotics in 5 days, abscess > 5cm, or left lobe involvement
Línea 97:		Línea 105:


	==Disposition==		==Disposition== <!--T:20-->

			<!--T:21-->
	*'''Admission'''		*'''Admission'''
	**Admit if signs of shock, sepsis, or peritonitis		**Admit if signs of shock, sepsis, or peritonitis
Línea 107:		Línea 116:


	==External Links==		==External Links== <!--T:22-->

			<!--T:23-->
	*[https://www.merckmanuals.com/professional/infectious-diseases/intestinal-protozoa-and-microsporidia/amebiasis?query=amebiasis Merk Manual - Amebiasis]		*[https://www.merckmanuals.com/professional/infectious-diseases/intestinal-protozoa-and-microsporidia/amebiasis?query=amebiasis Merk Manual - Amebiasis]



	==References==		==References== <!--T:24-->

			<!--T:25-->
	<references/>		<references/>

			<!--T:26-->
	[[Category:ID]]		[[Category:ID]]
	[[Category:Tropical Medicine]]		[[Category:Tropical Medicine]]

Ostermayer: Prepared the page for translation

2026-01-04T21:38:39Z

Prepared the page for translation

← Revisión anterior		Revisión del 21:38 4 ene 2026
Línea 1:		Línea 1:
	<languages/>		<languages/>
	<translate>		<translate>


	==Background==		==Background==
Línea 11:		Línea 12:
	*[[Special:MyLanguage/Liver abscess\|Liver abscess]] - 10x more common in men		*[[Special:MyLanguage/Liver abscess\|Liver abscess]] - 10x more common in men
	*Incubation period usually 2-4 weeks, but may range from a few days to years		*Incubation period usually 2-4 weeks, but may range from a few days to years



Línea 21:		Línea 23:
	**Abscess rupture can involve associated peritoneum, pericardium, or pleural cavity		**Abscess rupture can involve associated peritoneum, pericardium, or pleural cavity
	*Extrahepatic amebic abscesses in the lung, brain, and skin are rare		*Extrahepatic amebic abscesses in the lung, brain, and skin are rare



Línea 42:		Línea 45:
	{{Diarrhea DDX}}		{{Diarrhea DDX}}
	<translate>		<translate>



Línea 59:		Línea 63:
	*Stool, serum, or abscess fluid antigen		*Stool, serum, or abscess fluid antigen
	*Indirect hemagglutination (antibody)		*Indirect hemagglutination (antibody)



Línea 67:		Línea 72:
	*Abdominal CT		*Abdominal CT
	**Alternative to ultrasound; equally effective in identifying abscess		**Alternative to ultrasound; equally effective in identifying abscess



Línea 75:		Línea 81:

	*[[Special:MyLanguage/Paromomycin\|Paromomycin]] or diloxanide		*[[Special:MyLanguage/Paromomycin\|Paromomycin]] or diloxanide



Línea 80:		Línea 87:

	*[[Special:MyLanguage/Metronidazole\|Metronidazole]]		*[[Special:MyLanguage/Metronidazole\|Metronidazole]]



Línea 86:		Línea 94:
	*[[Special:MyLanguage/Flagyl\|Flagyl]], [[Special:MyLanguage/tinidazole\|tinidazole]], [[Special:MyLanguage/paromomycin\|paromomycin]], or diloxanide		*[[Special:MyLanguage/Flagyl\|Flagyl]], [[Special:MyLanguage/tinidazole\|tinidazole]], [[Special:MyLanguage/paromomycin\|paromomycin]], or diloxanide
	*Consider drainage of abscess by IR if no response to antibiotics in 5 days, abscess > 5cm, or left lobe involvement		*Consider drainage of abscess by IR if no response to antibiotics in 5 days, abscess > 5cm, or left lobe involvement



Línea 95:		Línea 104:
	*'''Discharge'''		*'''Discharge'''
	**Patients who are non-toxic and able to tolerate oral hydration/PO meds can be discharged with outpatient follow-up		**Patients who are non-toxic and able to tolerate oral hydration/PO meds can be discharged with outpatient follow-up



Línea 100:		Línea 110:

	*[https://www.merckmanuals.com/professional/infectious-diseases/intestinal-protozoa-and-microsporidia/amebiasis?query=amebiasis Merk Manual - Amebiasis]		*[https://www.merckmanuals.com/professional/infectious-diseases/intestinal-protozoa-and-microsporidia/amebiasis?query=amebiasis Merk Manual - Amebiasis]



Línea 109:		Línea 120:
	[[Category:Tropical Medicine]]		[[Category:Tropical Medicine]]
	[[Category:GI]]		[[Category:GI]]

	</translate>		</translate>

Ostermayer: Prepared the page for translation

2026-01-04T21:37:35Z

Prepared the page for translation

← Revisión anterior		Revisión del 21:37 4 ene 2026
Línea 1:		Línea 1:
			<languages/>
			<translate>

	==Background==		==Background==

	[[File:Amebiasis LifeCycle.gif\|thumb\|The life-cycle of various intestinal Entamoeba species.]]		[[File:Amebiasis LifeCycle.gif\|thumb\|The life-cycle of various intestinal Entamoeba species.]]
	*Fecal oral transmission of Entamoeba histolytica cyst		*Fecal oral transmission of Entamoeba histolytica cyst
Línea 5:		Línea 9:
	*Excystation in intestinal lumen		*Excystation in intestinal lumen
	*Trophozoites adhere and colonizes large intestine forming new cysts or invade the intestinal mucosa to cause colitis or abscesses		*Trophozoites adhere and colonizes large intestine forming new cysts or invade the intestinal mucosa to cause colitis or abscesses
	*[[Liver abscess]] - 10x more common in men		*[[Special:MyLanguage/Liver abscess\|Liver abscess]] - 10x more common in men
	*Incubation period usually 2-4 weeks, but may range from a few days to years		*Incubation period usually 2-4 weeks, but may range from a few days to years


	==Clinical Features==		==Clinical Features==

	*Asymptomatic vs. dysentery vs. extraintestinal abscesses		*Asymptomatic vs. dysentery vs. extraintestinal abscesses
	*Intestinal- several weeks of crampy [[abdominal pain]], weight loss, watery or bloody [[diarrhea]]		*Intestinal- several weeks of crampy [[Special:MyLanguage/abdominal pain\|abdominal pain]], weight loss, watery or bloody [[Special:MyLanguage/diarrhea\|diarrhea]]
	*[[Liver abscess]]-[[fever]], [[cough]], [[RUQ pain\|RUQ]] or [[epigastric pain]], right-sided [[chest pain\|pleural pain]] or referred shoulder pain +/- GI upset		*[[Special:MyLanguage/Liver abscess\|Liver abscess]]-[[Special:MyLanguage/fever\|fever]], [[Special:MyLanguage/cough\|cough]], [[Special:MyLanguage/RUQ pain\|RUQ]] or [[Special:MyLanguage/epigastric pain\|epigastric pain]], right-sided [[Special:MyLanguage/chest pain\|pleural pain]] or referred shoulder pain +/- GI upset
	**[[Hepatomegaly]] with tenderness over the liver a typical finding		**[[Special:MyLanguage/Hepatomegaly\|Hepatomegaly]] with tenderness over the liver a typical finding
	**Abscess rupture can involve associated peritoneum, pericardium, or pleural cavity		**Abscess rupture can involve associated peritoneum, pericardium, or pleural cavity
	*Extrahepatic amebic abscesses in the lung, brain, and skin are rare		*Extrahepatic amebic abscesses in the lung, brain, and skin are rare


	==Differential Diagnosis==		==Differential Diagnosis==


	===Dysentery===		===Dysentery===
	*Infectious- [[shigella]], [[salmonella]], [[campylobacter]], [[E. Coli]].
	*Noninfectious- [[Inflammatory bowel disease]], [[ischemic colitis]], [[diverticulitis]], AV malformation.

			*Infectious- [[Special:MyLanguage/shigella\|shigella]], [[Special:MyLanguage/salmonella\|salmonella]], [[Special:MyLanguage/campylobacter\|campylobacter]], [[Special:MyLanguage/E. Coli\|E. Coli]].
			*Noninfectious- [[Special:MyLanguage/Inflammatory bowel disease\|Inflammatory bowel disease]], [[Special:MyLanguage/ischemic colitis\|ischemic colitis]], [[Special:MyLanguage/diverticulitis\|diverticulitis]], AV malformation.

			</translate>
	{{Liver abscess DDX}}		{{Liver abscess DDX}}
			<translate>

			</translate>
	{{Fever in Traveler DDX}}		{{Fever in Traveler DDX}}
			<translate>

			</translate>
	{{Diarrhea DDX}}		{{Diarrhea DDX}}
			<translate>


	==Evaluation==		==Evaluation==


	===Labs===		===Labs===

	*CBC		*CBC
	*Chem		*Chem
	*[[LFTs]]		*[[Special:MyLanguage/LFTs\|LFTs]]
	*Stool PCR		*Stool PCR
	**Diagnostic gold standard		**Diagnostic gold standard
Línea 39:		Línea 59:
	*Stool, serum, or abscess fluid antigen		*Stool, serum, or abscess fluid antigen
	*Indirect hemagglutination (antibody)		*Indirect hemagglutination (antibody)


	===Imaging===		===Imaging===

	*Abdominal Ultrasound		*Abdominal Ultrasound
	**58-98% SN for liver abscess (depending on size/location)		**58-98% SN for liver abscess (depending on size/location)
	*Abdominal CT		*Abdominal CT
	**Alternative to ultrasound; equally effective in identifying abscess		**Alternative to ultrasound; equally effective in identifying abscess


	==Management==		==Management==


	===Asymptomatic colonization===		===Asymptomatic colonization===
	*[[Paromomycin]] or diloxanide
			*[[Special:MyLanguage/Paromomycin\|Paromomycin]] or diloxanide


	===Colitis===		===Colitis===
	*[[Metronidazole]]
			*[[Special:MyLanguage/Metronidazole\|Metronidazole]]


	===Liver abscess===		===Liver abscess===
	*[[Flagyl]], [[tinidazole]], [[paromomycin]], or diloxanide
			*[[Special:MyLanguage/Flagyl\|Flagyl]], [[Special:MyLanguage/tinidazole\|tinidazole]], [[Special:MyLanguage/paromomycin\|paromomycin]], or diloxanide
	*Consider drainage of abscess by IR if no response to antibiotics in 5 days, abscess > 5cm, or left lobe involvement		*Consider drainage of abscess by IR if no response to antibiotics in 5 days, abscess > 5cm, or left lobe involvement


	==Disposition==		==Disposition==

	*'''Admission'''		*'''Admission'''
	**Admit if signs of shock, sepsis, or peritonitis		**Admit if signs of shock, sepsis, or peritonitis
Línea 63:		Línea 95:
	*'''Discharge'''		*'''Discharge'''
	**Patients who are non-toxic and able to tolerate oral hydration/PO meds can be discharged with outpatient follow-up		**Patients who are non-toxic and able to tolerate oral hydration/PO meds can be discharged with outpatient follow-up


	==External Links==		==External Links==

	*[https://www.merckmanuals.com/professional/infectious-diseases/intestinal-protozoa-and-microsporidia/amebiasis?query=amebiasis Merk Manual - Amebiasis]		*[https://www.merckmanuals.com/professional/infectious-diseases/intestinal-protozoa-and-microsporidia/amebiasis?query=amebiasis Merk Manual - Amebiasis]


	==References==		==References==

	<references/>		<references/>

Línea 73:		Línea 109:
	[[Category:Tropical Medicine]]		[[Category:Tropical Medicine]]
	[[Category:GI]]		[[Category:GI]]
			</translate>

Rossdonaldson1: /* Evaluation */

2021-07-24T13:21:59Z

Evaluation

← Revisión anterior		Revisión del 13:21 24 jul 2021
Línea 28:		Línea 28:

	==Evaluation==		==Evaluation==
	*'''Labs~~'''~~		===Labs===
	**CBC		*CBC
	**Chem		*Chem
	**[[LFTs]]		*[[LFTs]]
	**Stool PCR		*Stool PCR
	***Diagnostic gold standard		**Diagnostic gold standard
	***100% sensitive and specific		**100% sensitive and specific
	**Stool or abscess microscopy		*Stool or abscess microscopy
	***<60% SN; unreliable diagnostic test<ref>Rayan HZ. Microscopic overdiagnosis of intestinal amoebiasis. J Egypt Soc Parasitol. 2005;35(3):941–951</ref>		**<60% SN; unreliable diagnostic test<ref>Rayan HZ. Microscopic overdiagnosis of intestinal amoebiasis. J Egypt Soc Parasitol. 2005;35(3):941–951</ref>
	**Stool, serum, or abscess fluid antigen		*Stool, serum, or abscess fluid antigen
	**Indirect hemagglutination (antibody)		*Indirect hemagglutination (antibody)

			===Imaging===
	*'''Imaging~~'''~~		*Abdominal Ultrasound
	**Abdominal Ultrasound		**58-98% SN for liver abscess (depending on size/location)
	***58-98% SN for liver abscess (depending on size/location)		*Abdominal CT
	**Abdominal CT		**Alternative to ultrasound; equally effective in identifying abscess
	***Alternative to ultrasound; equally effective in identifying abscess

	==Management==		==Management==

Blsimpso at 03:02, 24 July 2021

2021-07-24T03:02:13Z

← Revisión anterior		Revisión del 03:02 24 jul 2021
Línea 64:		Línea 64:
	*'''Discharge'''		*'''Discharge'''
	**Patients who are non-toxic and able to tolerate oral hydration/PO meds can be discharged with outpatient follow-up		**Patients who are non-toxic and able to tolerate oral hydration/PO meds can be discharged with outpatient follow-up

			==External Links==
			*[https://www.merckmanuals.com/professional/infectious-diseases/intestinal-protozoa-and-microsporidia/amebiasis?query=amebiasis Merk Manual - Amebiasis]

	==References==		==References==

Blsimpso: /* Disposition */

2021-07-24T02:56:00Z

Disposition

← Revisión anterior		Revisión del 02:56 24 jul 2021
Línea 59:		Línea 59:

	==Disposition==		==Disposition==
	*~~Home~~ if ~~no complications~~		*'''Admission'''
			**Admit if signs of shock, sepsis, or peritonitis
			**Patients with toxic megacolon should be admitted for surgical intervention.
			*'''Discharge'''
			**Patients who are non-toxic and able to tolerate oral hydration/PO meds can be discharged with outpatient follow-up

	==References==		==References==

Blsimpso at 02:43, 24 July 2021

2021-07-24T02:43:07Z

← Revisión anterior		Revisión del 02:43 24 jul 2021
Línea 27:		Línea 27:
	{{Diarrhea DDX}}		{{Diarrhea DDX}}

	~~<nowiki>Insert non-formatted text here</nowiki>~~==Evaluation==		==Evaluation==
	*'''Labs'''		*'''Labs'''
	**CBC		**CBC

Blsimpso: /* Evaluation */

2021-07-24T02:40:31Z

Evaluation

← Revisión anterior		Revisión del 02:40 24 jul 2021
Línea 27:		Línea 27:
	{{Diarrhea DDX}}		{{Diarrhea DDX}}

	==Evaluation==		<nowiki>Insert non-formatted text here</nowiki>==Evaluation==
	*CBC		*'''Labs'''
	*Chem		**CBC
	*[[LFTs]]		**Chem
	*Stool or abscess microscopy		**[[LFTs]]
	*Stool, serum, or abscess fluid antigen		**Stool PCR
	*Indirect hemagglutination (antibody)		***Diagnostic gold standard
	*CT or ultrasound ~~for suspected~~ abscess		***100% sensitive and specific
			**Stool or abscess microscopy
			***<60% SN; unreliable diagnostic test<ref>Rayan HZ. Microscopic overdiagnosis of intestinal amoebiasis. J Egypt Soc Parasitol. 2005;35(3):941–951</ref>
			**Stool, serum, or abscess fluid antigen
			**Indirect hemagglutination (antibody)


			*'''Imaging'''
			**Abdominal Ultrasound
			***58-98% SN for liver abscess (depending on size/location)
			**Abdominal CT
			***Alternative to ultrasound; equally effective in identifying abscess

	==Management==		==Management==

Rossdonaldson1: /* Background */

2021-07-07T18:24:07Z

Background

← Revisión anterior		Revisión del 18:24 7 jul 2021
Línea 1:		Línea 1:
	==Background==		==Background==
			[[File:Amebiasis LifeCycle.gif\|thumb\|The life-cycle of various intestinal Entamoeba species.]]
	*Fecal oral transmission of Entamoeba histolytica cyst		*Fecal oral transmission of Entamoeba histolytica cyst
	*Most infection asymptomatic		*Most infection asymptomatic