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*No specific therapy for most; self-limited
*[[NSAIDS]] and cool liquids for pain
*Encourage good hand hygiene to prevent spread
*Some recommend [[Magic Mouthwash]]/oral [[lidocaine]] if not tolerating PO intake, although evidence suggests no better than placebo<ref>Hopper S. et al. Topical lidocaine to improve oral intake in children with painful infectious mouth ulcers: a blinded, randomized, placebo-controlled trial. Ann Emerg Med. 2014 Mar;63(3):292-9</ref>

;In infants, do NOT use oral lidocaine due to risk of [[lidocaine toxicity]] and FDA black box warning<ref>FDA recommends not using lidocaine to treat teething pain. http://www.fda.gov/Drugs/DrugSafety/ucm402240.htm</ref><ref>Curtis LA, Dolan TS, Seibert HE. Are one or two dangerous? Lidocaine and topical anesthetic exposures in children. J Emerg Med 2009;37:32-39</ref>