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==Contraindications==
===Absolute<ref>Graham, A.S., et al. Central Venous Catheterization. N Engl J Med 2007;356:e21</ref>===
*Infection over the placement site
*Anatomic obstruction (thrombosis of target vein, other anatomic variance)
*Site-specific
**Subclavian - trauma/fracture to ipsilateral clavicle or proximal ribs

===Relative===
*[[Coagulopathy]] (see below)
*Distortion of landmarks by trauma or congenital anomalies
*Prior vessel injury or procedures
*Morbid obesity
*Uncooperative/combative patient

{{Central line with coagulopathy}}