Ver el código de «Template:Antibiotics Open Fracture/es»

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===Antibióticos Profilácticos para [[Special:MyLanguage/Open fractures|Fracturas abiertas]]===

''Iniciar lo más pronto posible; tasa de infección aumentada cuando se retrasa<ref>Gosselin RA, et al. Antibiotics for preventing infection in open limb fractures. Cochrane Database Syst Rev. 2004; (1):CD003764.</ref>''


====Opciones para [[Special:MyLanguage/Open_fracture|Fracturas Grado I y II]]====

*[[Special:MyLanguage/Cefazolin|Cefazolin]] (Ancef) 2 g IV (inmediatamente y cada 8 horas x 3 dosis totales)<ref name=Garner2020>Garner MR, et al. Antibiotic Prophylaxis in Open Fractures: Evidence, Evolving Issues, and Recommendations. Journal of the American Academy of Orthopaedic Surgeons. April 15, 2020. 28(8):309-315</ref>
*Alergia a cefalosporina: [[Special:MyLanguage/clindamycin|clindamicina]] 900 mg IV (inmediatamente y cada 8 horas x 3 dosis totales)<ref name=Garner2020>Garner MR, et al. Antibiotic Prophylaxis in Open Fractures: Evidence, Evolving Issues, and Recommendations. Journal of the American Academy of Orthopaedic Surgeons. April 15, 2020. 28(8):309-315</ref>


====Opciones para [[Special:MyLanguage/Open_fracture#Grade_III|Fractura Grado III]]====

*[[Special:MyLanguage/Ceftriaxone|Ceftriaxona]] 2 g IV (inmediatamente x 1 dosis total) MÁS [[Special:MyLanguage/vancomycin|vancomicina]] 1 g IV (inmediatamente y cada 12 horas x 2 dosis totales)<ref name=Garner2020>Garner MR, et al. Antibiotic Prophylaxis in Open Fractures: Evidence, Evolving Issues, and Recommendations. Journal of the American Academy of Orthopaedic Surgeons. April 15, 2020. 28(8):309-315</ref>
*Alergia a cefalosporina: [[Special:MyLanguage/aztreonam|aztreonam]] 2 g IV (inmediatamente y cada 8 horas x 3) MÁS [[Special:MyLanguage/vancomycin|vancomicina]] 1 g IV (inmediatamente y cada 12 horas x 2 dosis totales)<ref name=Garner2020>Garner MR, et al. Antibiotic Prophylaxis in Open Fractures: Evidence, Evolving Issues, and Recommendations. Journal of the American Academy of Orthopaedic Surgeons. April 15, 2020. 28(8):309-315</ref>


====Consideraciones Especiales====

*Preocupación por [[Special:MyLanguage/clostridium|clostridium]] (contaminación por tierra, lesiones agrícolas, posible contaminación intestinal): agregar adicionalmente [[Special:MyLanguage/penicillin|penicilina]]<ref>HoffWS, Bonadies JA, Cachecho R, Dorlac WC: East practice management guidelines work group: Update to practice management guidelines for prophylactic antibiotic use in open fractures. J Trauma 2011;70:751-754.</ref><ref name=Garner2020>Garner MR, et al. Antibiotic Prophylaxis in Open Fractures: Evidence, Evolving Issues, and Recommendations. Journal of the American Academy of Orthopaedic Surgeons. April 15, 2020. 28(8):309-315</ref>
*Heridas con agua dulce: [[Special:MyLanguage/fluoroquinolones|fluoroquinolonas]] O cefalosporina de 3ra/4ta generación
*Heridas con agua salada ([[Special:MyLanguage/vibrio|vibrio]]): [[Special:MyLanguage/doxycycline|doxiciclina]] + [[Special:MyLanguage/ceftazidime|ceftazidima]] O [[Special:MyLanguage/fluoroquinolone|fluoroquinolona]]