Ver el código de «Sheehan's syndrome»

==Background==
[[File:1806 The Hypothalamus-Pituitary Complex.jpg|thumb|Pituitary gland anatomic relations.]]
[[File:Pituiary gland - regulatory hormones.png|thumb|Pitutiary gland physiology.]]
*Also known as postpartum hypopituitarism
*Caused by pituitary hypoperfusion and infarction usually in the setting of [[postpartum hemorrhage]]
*During pregnancy there is enlargement of the pituitary gland predisposing it to ischemia in low-flow states

==Clinical Features==
*Symptoms consistent with [[adrenal insufficiency]], [[hypothyroidism]] and [[hypogonadism]]
**Inability to lactate
**Amenorrhea or oligomenorrhea
**Fatigue
**Cold intolerance
**Lethargy
**Weight loss
*Can occur any time from the immediate postpartum period to years after birth

==Differential Diagnosis==
{{Adrenal crisis ddx}}

==Evaluation==
*Evaluation of serum prolactin levels is not performed as it is difficult to differentiate low from normal serum prolactin levels
===Workup===
*Workup should include testing of all anterior pituitary hormones
*Patients should be evaluated and treated for adrenal insufficiency immediately as this can worsen pre-existing hypotension 
*Other pituitary hormones can be tested for 4-6 weeks after the initial insult

===Diagnosis===

==Management==
*Currently no treatment is available but there is an ongoing small open-label pilot study looking at using recombinant human prolactin

==Disposition==


==See Also==
*[[Pregnancy]]
*[[Pituitary apoplexy]]

==External Links==


==References==
<references/>

[[Category:Endocrinology]]
[[Category:OBGYN]]