Ver el código de «Q fever»

==Background==
*Described in 1937: occupational disease of abattoir workers (manage animals before and after slaughtering process) and dairy farmers
*Caused by Coxiella burnetii
**Obligate intracellular bacteria morphologically similar to Rickettsia
**Reservoirs include cattle, goat, sheep, and ticks (Dermacentor andersoni)
*CDC: category B biologic warfare agent due to its inhaled infectivity
*Worldwide disease

==Clinical Features==
*Symptoms usually develop within 2-3 weeks, although up to half of those infected may not show symptoms
**high [[fevers]] (up to 104-105°F)
**severe [[headache]]
**general malaise
**myalgias
**chills/sweats
**non-productive cough
**[[nausea/vomiting]]
**[[diarrhea]]
**[[abdominal pain]]
**[[chest pain]]
*Complications include [[pneumonia]], granulomatous hepatitis (inflammation of the liver), [[myocarditis]] (inflammation of the heart tissue), and central nervous system complications.
*[[Endocarditis]] is the major form of chronic disease
*Infection in pregnancy is more likely to be asymptomatic, but often results in chronic Q fever and obstetrical complications

==Differential Diagnosis==
{{Fever in Traveler DDX}}

{{Lower respiratory zoonotic infections}}

==Evaluation==
*CBC, Complete Metabolic Panel – Liver enzymes usually elevated 2-10 times normal
*[[Blood cultures]]
*[[CXR]]

==Management==
*[[Doxycycline]]
**Adults: 100mg BID
**Children < 45 kg: 2.2mg/kg BID
*Patients should be treated for at least 3 days after the fever subsides and until there is evidence of clinical improvement. Standard duration of treatment is 2-3 weeks.

==Disposition==
*Most patients require admission for further workup

==See Also==

==External Links==

==References==
<references/>
*http://www.cdc.gov/qfever/ 
*http://www.ncbi.nlm.nih.gov/pubmed/16168313

[[Category:ID]]