Ver el código de «Purpura fulminans»

==Background==
{{Skin anatomy background images}}
*Life-threatening syndrome of intravascular coagulation and hemmorrhagic skin infarction→ [[DIC]] and vascular collapse
*Usually occurs in children, but can occur in adults
*Most commonly in the setting of overwhelming sepsis '''OR''' 7-10 days after infection

===Causes===
*[[Meningococcus]]
*[[Streptococcus]] species
*[[Varicella]]
*[[Rickettsia sp]]
*Venom-induced consumptive coagulopathy (VICC) due to [[snake bites]]
*Protein C, protein S, or antithrombin III deficiency
*Drug-induced

==Clinical Features==
[[File:Baby_purpura.png|thumb|Neonatal purpura fulminans]]
[[File:PurpuraFulminans.png|thumb|Purpura fulminans]]
*Erythematous [[rash|macules]] rapidly progress→ Large, purpuric lesions
*[[DIC]]
*[[Hypotension]]
*[[Fever]]

==Differential Diagnosis==
{{Purpura DDX by findings}}

==Evaluation==
*[[DIC]] work up
**CBC, PT/PTT, fibrinogen, d-dimer, FDP
*Infectious work up

==Management==
*Treat [[shock]]
*Treat underlying infection
*Necrotic tissue may require debridement
*[[Coagulopathy]] correction, in some cases
**Typically only if bleeding or need for procedure
***Exception: [[FFP]] usually indicated for neonatal purpura fulminans
**[[Cryoprecipitate]]: consider if fibrinogen <100
**[[Platelets]]: consider repletion if <50K with bleeding or <20K without bleeding
**[[FFP]]: consider repletion to goal of PT and PTT < 1.5 times the normal limit
**[[Vitamin K]], [[folate]]

==Disposition==
*Admit!
==See Also==
*[[Coagulopathy (Main)]]
*[[DIC]]

==External Links==

==References==
<references/>

[[Category:Dermatology]] [[Category:ID]]