Ver el código de «Prochlorperazine»

==General==
*Type: [[anti-psychotic]] and [[antiemetics|anti-emetic]]
*Dosage Forms: 5, 10
*Routes of Administration: IV, PO
*Common Trade Names: Compazine

==Adult Dosing==
===[[Headache]]===
*10mg IV (slow push or in 1L [[IVF]])

===[[Nausea/Vomiting]]===
*5-10mg PO or IV q6-8 hours
*Max: 40mg/day

==Pediatric Dosing==
===[[Nausea and vomiting (peds)|Nausea/vomiting]], severe===
====2 yo and older, 9-14 kg====
*2.5mg PO q12-24 h; Max 7.5mg/day

====2 yo and older, 14-18 kg====
*2.5mg PO q8-12 h; Max 10mg/day

====2 yo and older, 18-39 kg====
*2.5mg PO q8 hr; Max 15mg/day

====2 yo and older, >39 kg====
*5mg PO q6-8 h, Max: 20mg/day

===Schizophrenia===
====2-5 yo====
*2.5 - 5mg PO q6-8 hr, Max 20mg/day
====6-12 yo====
*2.5-5mg PO q6-8 hr, Max 25mg/day

==Special Populations==
*[[Drug Ratings in Pregnancy|Pregnancy Rating]]: Pregnancy category C
*[[Lactation risk categories|Lactation risk]]: Safety unknown
*Renal Dosing: not defined
*Hepatic Dosing: not defined

==Contraindications==
*Allergy to class/drug

==Adverse Reactions==
===Serious===
*tardive dyskinesia
*neuroleptic malignant syndrome
*blood dyscrasias
*agranulocytosis
*thrombocytopenic purpura
*orthostatic hypotension
*extrapyramidal symptoms
*cholestatic jaundice
*hepatotoxicity
*QT prolongation
*cardiac arrest
*seizures
*anaphylactoid reactions
*lupus erythematosus
*priapism
*heat stroke
*neonatal extrapyramidal symptoms (3rd trimester use)
*neonatal withdrawal symptoms (3rd trimester use)

===Common===
*[[Akathisia]]
*drowsiness
*dizziness
*blurred vision
*xerostomia
*constipation
*urinary retention
*headache
*nasal congestion
*nausea
*menstrual irregularities
*amenorrhea
*weight gain
*hyperprolactinemia
*hyperglycemia
*hypoglycemia
*insomnia
*agitation
*sexual dysfunction
*photosensitivity
*impaired body temperature regulation

==Pharmacology==
*Half-life: 3-5 hrs (oral); 7 hrs (IV)
*Metabolism: liver extensively, GI tract
*Excretion: urine, bile/feces
*Mechanism of Action: selectively antagonizes dopamine D2 receptors

==Comments==


==Indications by Condition==
''The following table is automatically generated from disease/condition pages across WikEM.''

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 |?Has Indication=Indication
 |?Has Dose=Dose
 |?Has Context=Context
 |?Has Route=Route
 |?Has Population=Population
 |format=table
 |headers=plain
 |mainlabel=-
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}}

==See Also==
*[[Antipsychotic toxicity]]

==References==
<references/>
[[Category:Pharmacology]]