Ver el código de «Phentolamine»

==Administration==
*Type: [[Alpha 1 Blocker]]; [[Antidote]], Extravasation; [[Antihypertensive]]
*Routes of Administration: IV, IM
*Common Trade Names: OraVerse

==Adult Dosing==
*Pheochromocytomectomy adjunct: 5mg IM/IV q2-4h PRN
**Start: 1-2h preop

*Extravasation (norepinephrine-associated): 5-10mg injected into affected area x1
**Start: within 12h of extravasation

*[[Hypertensive crisis]]: 5mg IM/IV q2-4h PRN

==Pediatric Dosing==
*Pheochromocytomectomy adjunct: 1mg IM/IV q2-4h PRN
**Start: 1-2h preop

==Special Populations==
*[[Drug ratings in pregnancy|Pregnancy Risk]] Factor: C

===Renal Dosing===
*No dosing adjustments

===Hepatic Dosing===
*No dosing adjustments

==Contraindications==
*Hypersensitivity to phentolamine or components
*[[MI]]
*CAD
*Angina
*Caution if PUD

==Adverse Reactions==
===Serious===
*[[MI]]
*[[stroke]]
*hypotension, severe
*[[arrhythmias]]
*PUD
*[[priapism]]

===Common===
*tachycardia
*[[weakness]]
*[[dizziness]]
*flushing
*orthostatic hypotension
*nasal congestion
*[[nausea]]
*[[vomiting]]
*[[diarrhea]]

==Pharmacology==
*Half-life: 19 minutes
*Metabolism: Urine
*Excretion: CYP450

==Mechanism of Action==
*[[alpha 1 Blocker|α antagonist]]

==Indications by Condition==
''The following table is automatically generated from disease/condition pages across WikEM.''

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 |?Has Indication=Indication
 |?Has Dose=Dose
 |?Has Context=Context
 |?Has Route=Route
 |?Has Population=Population
 |format=table
 |headers=plain
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==See Also==
*[[Vasopressors]]

==References==
<Epocrates, UpToDate>
[[Category:Pharmacology]]