Ver el código de «Opisthorchis viverrini»

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==Background==

[[File:Opisthorchis LifeCycle.gif|thumb|Lifecycle of Opisthorchis.]]
*a.k.a. "southeast asian liver fluke" (endemic)
*Trematode
*Also within genus: opisthorchis felineus (Europe/Asia incl Russia) <ref name="CDC"> http://www.cdc.gov/dpdx/opisthorchiasis/ </ref>


===Life Cycle===

*Eggs pass in feces → freshwater snail ingestion → larval trematode embeds in fish skin/flesh → Fish consumed raw → duodenal cyst and subsequent biliary infection
*Fluke count may effect clinical presentation (lower counts more asymptomatic)


===Risk Factors===

*Exposure to endemic areas (see above)
*Consumption of raw/undercooked fish


===Clinical significance===

*May have acute infectious phase
*Source of mild and moderate GI disease
*Chronic infection predisposes to cholangitis, cholcystitis, cholangiocarcinoma (rare)


==Clinical Features==

*Mild: [[Special:MyLanguage/dyspepsia|dyspepsia]], [[Special:MyLanguage/diarrhea|diarrhea]], [[Special:MyLanguage/abdominal pain|abdominal pain]], [[Special:MyLanguage/constipation|constipation]]
*Moderate: [[Special:MyLanguage/hepatomegaly|hepatomegaly]], [[Special:MyLanguage/malnutrition|malnutrition]]
*<I>Felineus</I> species may have an acute phase: alike to [[Special:MyLanguage/schistosomiasis|schistosomiasis]] ([[Special:MyLanguage/fever|fever]], facial edema, [[Special:MyLanguage/lymphadenopathy|lymphadenopathy]], [[Special:MyLanguage/arthralgia|arthralgia]]s, [[Special:MyLanguage/rash|rash]], and [[Special:MyLanguage/eosinophilia|eosinophilia]]) and involvement may extend to pancreatic duct in chronic cases


==Differential Diagnosis==

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{{Helminth Types}}
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==Evaluation==


==Management==

*[[Special:MyLanguage/Praziquantel|Praziquantel]], 75mg/kg/day orally for 2 days (adults/pediatric) with meal<ref name="CDC" />
or
*[[Special:MyLanguage/Albendazole|Albendazole]], 10mg/kg/day orally for 7 days (adults/pediatric) with meal [non-FDA alternative]<ref name="CDC" />

*Identical to treatment for Clonorchis <ref name = "CDC2"> http://www.cdc.gov/dpdx/clonorchiasis/tx.html </ref>
*In cases of clonorchis in China, [[Special:MyLanguage/Trebindamine|Trebindamine]] 400mg once has less side effects and equal efficacy (not available in U.S.) <ref name="IDC"> http://pusware.com/testpus/bug_Clonorchis.html</ref> <ref name = "Trebindamine">http://www.ncbi.nlm.nih.gov/pubmed/23223597</ref>


==See Also==

*[[Special:MyLanguage/Helminth infections|Helminth infections]]


==References==

<references/>

[[Category:Tropical Medicine]]
[[Category:ID]]
[[Category:GI]]
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