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==Mechanism of Action==
*Nucleoside analoges are a class of antiviral medications that mimic the structure of natural nucleosides, interfering with viral DNA or RNA synthesis
*Primarily used for treatment of herpesvirus infections (e.g., HSV, VZV), HIV, hepatitis B and C, and some other viral infections
*Work by being incorporated into viral nucleic acids, leading to chain termination or mutagenesis

==Adverse Effects==
===Common===
*Nausea, vomiting, diarrhea
*Headache, fatigue
*Rash or pruritus
*Bone marrow suppression (e.g., zidovudine)

===Serious===
*Neurotoxicity (e.g., [[cidofovir]], [[tenofovir]])
*Nephrotoxicity (e.g., [[acyclovir]] in renal impairment)
*Lactic acidosis and hepatotoxicity (e.g., nucleoside reverse transcriptase inhibitors like [[zidovudine]])
*Bone density loss (e.g., [[tenofovir]])
*Teratogenicity (e.g., [[ribavirin]] contraindicated in pregnancy)

==List of Nucleoside analoges==
{{#ask:[[Is DrugClass::nucleoside analoge]] |format=ul }}

==See Also==
*[[Antiretrovirals]]
*[[HIV]]
*[[Hepatitis B]]

==References==
<references/>

[[Category:Pharmacology]]