Ver el código de «Nadalol»

==Administration==
*Type: [[beta blocker]]
*Dosage Forms:
*Routes of Administration: PO
*Common Trade Names: 

==Adult Dosing==
*40-160mg PO daily

==Pediatric Dosing==


==Special Populations==
===[[Drug pregnancy categories|Pregnancy Rating]]===
*C

===Lactation risk===
*Excreted in breastmilk. AAP says compatible with breastfeeding<ref>https://reference.medscape.com/drug/corgard-nadolol-342361#6</ref>

===Renal Dosing===
*CrCl 31-50 mL/min: Give q24-36hr
*CrCl 10-30 mL/min: Give q24-48hr
*CrCl <10 mL/min: Give q40-60hr===Hepatic Dosing===

==Contraindications==
*Allergy to class/drug
*Overt cardiac failure, 2°/3° heart block, cardiogenic shock
*Asthma/COPD
*Avoid during breastfeeding
*Sinus bradycardia
*Sick sinus syndrome without permanent pacemaker
*Caution if:
**Nonallergenic bronchospasm
**Cerebrovascular insufficiency
*Well-compensated CHF
*DM
**Hyperthyroidism/thyrotoxicosis
**Liver disease
**Renal impairment
**Peripheral vascular disease
**Planned surgery
**Pheochromocytoma
**Abrupt cessation may lead to worsened angina and myocardial infarction

==Adverse Reactions==
===Serious===
*Bronchospasm
*Hypotension

===Common===
*Drowsiness, insomnia
*Decreased sexual ability
*Bradycardia
*Dizziness, fatigue
*Hypotension
*Abdominal discomfort, constipation, diarrhea, nausea
*Cough, nasal congestion
*Bronchospasm
*Depression
*Decreased exercise tolerance
*Raynaud's phenomenon
*Increased triglycerides and insulin resistance, decreased HDL

May increase triglyceride levels and insulin resistance, and decrease HDL levels

==Pharmacology==
*Half-life: 10-24h
*Metabolism: none
*Excretion: urine

==Mechanism of Action==
*Blocks response to beta-adrenergic stimulation to beta1 and beta2 receptors; may reduce portal pressure through beta2 receptor, which reduces portal blood flow

==Comments==


==See Also==


==References==
<references/>

[[Category:Pharmacology]]
[[Category:Cardiology]]