Ver el código de «Myelophthistic anemia»

==Background==
*Form of normocytic [[anemia]]
*Associated with infiltrative disorder or bone marrow in the setting of malignancy--[[leukemia]], [[lymphoma]], granuloma

==Clinical Features==
*[[Anemia]] in patient with history of malignancy
*Pale skin
*[[Tachycardia]]/[[hypotension]] in severe cases
*[[hepatomegaly|Hepatosplenomegaly]] as sign of extra medullary hematopoiesis

==Differential Diagnosis==
*[[Aplastic anemia]]
*[[Myelofibrosis]]
*[[hemorrhage|Acute blood]] loss anemia
*Bone marrow suppression
*Anemia of chronic disease
*[[Hemolytic anemia]]

==Evaluation==
*Requires bone marrow biopsy
*Labs show normocytic anemia with decreased reticulocyte count
*Exam with signs of extra medullary hematopoiesis
*Index of suspicion in setting of malignancy

==Management==
*Identify anemia as emergent or non-emergent
*Evaluate for superimposed etiologies of anemia (Ie acute blood loss) and target treatment in the ED
*If emergent anemia get IV access, [[pRBCs|transfuse]] for signs of end organ damage--altered mental status, hypotension, chest pain, shortness of breath, decreased UOP
*Will need treatment of underlying malignancy to allow marrow recovery while supporting hemodynamics

==Disposition==
*Admit for bone marrow biopsy and treatment of underlying disease

==See Also==
*[[Anemia]]

==References==
*Rosen, Peter, John A. Marx, Robert S. Hockberger, and Ron M. Walls. "Anemia". Rosen's Emergency Medicine Concepts and Clinical Practice. 8th ed. Vol. 2. Philadelphia, PA: Elsevier/Saunders, 2013.
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[[Category:Heme/Onc]]