Ver el código de «Ketoconazole»

==Administration==
*Type: [[Antifungal]]
*Dosage Forms: Tablet, 200mg
*Routes of Administration: PO, topical
*Common Trade Names: Nizoral

==Adult Dosing==
===Fungal infections===
*200-400mg PO qday

===Prostate cancer===
*400mg PO q8h

==Pediatric Dosing==
===Fungal infectionss (2 years and up)===
*3.3-6.6mg/kg PO qday

==Special Populations==
*[[Drug Ratings in Pregnancy|Pregnancy Rating]]: C, adverse events have been seen in animal studies
*[[Lactation risk categories|Lactation risk]]: Excreted in breast milk, not recommended by manufacturer. 

===Renal Dosing===
*Adult: no adjustment
*Pediatric: no adjustment

===Hepatic Dosing===
*Adult: contraindicated in liver disease
*Pediatric: contraindicated in liver disease

==Contraindications==
*Allergy to class/drug

==Adverse Reactions==
===Serious===
*[[Hepatotoxicity]]
*[[Adrenal insufficiency]]
*[[Hypersensitivity reaction]]
*[[Anaphylaxis]]
*[[Thrombocytopenia]]
*[[Leukopenia]]
*[[Hemolytic anemia]]

===Common===
*[[Nausea]]
*[[Abdominal pain]]
*[[Dizziness]]
*[[Diarrhea]]
*[[Headache]]
*[[Pruritis]]
*[[Lethargy]]
*[[Gynecomastia]]

==Pharmacology==
*Half-life: 8 h
*Metabolism: Liver (CYP450)
*Excretion: feces > urine

==Mechanism of Action==
*Inhibits synthesis of cell membrane ergosterol

==Comments==

==See Also==
*[[Antifungals]]
*[[Fungal infections]]

==References==
<references/>
[[Category:Pharmacology]]
[[Category:ID]]