Ver el código de «INR»

==Background==
*International Normalized Ratio; standardized measure of the extrinsic coagulation pathway
*Based on prothrombin time (PT) corrected using an international sensitivity index

==Normal Values==
*Normal: 0.8-1.1
*Therapeutic anticoagulation (warfarin): typically 2.0-3.0 (mechanical valve: 2.5-3.5)

==Interpretation==
*Elevated INR: warfarin use, liver disease, DIC, vitamin K deficiency, factor VII deficiency
*Supratherapeutic INR on warfarin: hold warfarin, vitamin K (PO or IV), consider 4-factor PCC for serious bleeding<ref>Tomaselli GF, et al. 2020 ACC Expert Consensus Decision Pathway on Management of Bleeding in Patients on Oral Anticoagulants. J Am Coll Cardiol. 2020; 76(5):594-622. PMID 32680646.</ref>
*INR is not validated for assessing coagulation in patients on DOACs
*INR does not reliably predict bleeding risk in cirrhosis (due to balanced coagulopathy)

==See Also==
*[[PT]]
*[[Coagulation Studies]]
*[[Warfarin]]
*[[Vitamin K]]

==References==
<references/>

[[Category:Labs]]