Ver el código de «Granuloma inguinale»

==Background==
*"Donovanosis"
*''Klebsiella granulomatis'': Intracellular gram negative rod
*[[Sexually transmitted disease]]
*Tropical and semitropical (India, Papua New Guinea, Australia, Carribean, Africa)
*Very rare in the United States

==Clinical Features==
*Genital/perineal ulcer
**Chronic, painless, progressive 
**Irregular, clean-based, granulomatous, nodular
**Hard, bleeds easily
**"Beefy red"
* Inguinal lymphadenopathy is generally mild or absent
*Urethral stenosis
*Lymphatic obstruction, elephantiasis
*Hematogenous spread to spleen, lungs, liver, bones, orbits
[[File:Granuloma Inguinale.JPG|thumb]]

==Differential Diagnosis==
{{STD DDX}}

==Evaluation==
===Workup===
*Microscopy: Donovan bodies
**Short, pleomorphic rods with bipolar staining
*Screen for other [[STDs]]

==Management==
*The duration of treatment is a minimum of three weeks, and should be continued until all lesions have completely healed.
*Recommended: [[Azithromycin]] 1g PO qweek
*Alternative: 
**[[Doxycycline]] 100mg PO BID
**[[Ciprofloxacin]] 750mg PO BID
**[[Erythromycin]] base 500mg PO QID
**[[Bactrim DS]] (160mg/800mg) PO BID

==Disposition==
*Typically outpatient

==See Also==
*[[STDs]]
*[[Ulcerative STDs]]

==External Links==
https://www.cdc.gov/std/tg2015/donovanosis.htm

==References==
<references/>

[[Category:ID]]
[[Category:Tropical Medicine]]