Ver el código de «EBQ:Irrigation of Cutaneous Abscesses Does Not Improve Treatment Success»

{{JC info
| title= Irrigation of Cutaneous Abscesses Does Not Improve Treatment Success
| abbreviation= 
| expansion=
| published= 2016-3
| author= Chinnock B, Hendey G
| journal= Annals of Emergency Medicine
| year= 2016
| volume= 67
| issue= 3
| pages= 379-383
| pmid= 26416494
| fulltexturl= http://www.annemergmed.com/article/S0196-0644(15)01188-9/fulltext
| pdfurl= http://www.annemergmed.com/article/S0196-0644(15)01188-9/pdf
| status=Complete
}}
==Clinical Question==
Does irrigation of cutaneous abscesses in the ED reduce the need for further intervention?

==Conclusion==
'''Irrigation of cutaneous abscesses after standard incision and drainage does not decrease the need for further intervention, and may be unnecessary.'''

==Major Points==
The treatment of cutaneous [[abscesses]] classically involves the [[incision and drainage]] procedure.  Historically, this procedure involves making a linear incision over the [[abscess]] cavity, followed by manual expression of cavity contents, blunt dissection to break up loculations, further irrigation with saline, and packing with gauze.  However, a lack of data supports the routine use of irrigation to improve the success of the procedure and treatment of the abscess.  In addition, while not typically considered, the routine use of irrigation does include some downsides: extra time and supplies, cost, and the possibility of microbiologic contamination of the patient care area and body fluid exposure to the practitioner.

The authors of this study randomized patients to I&D with or without irrigation to determine which method best treated cutaneous abscesses.  While there were some differences in the baseline characteristics of the study (higher incidence of packing and [[antibiotic]] usage in the Irrigation Group), these differences would presumably improve the outcomes of these patients; a finding that was not demonstrated. '''Ultimately, the authors concluded that irrigation of cutaneous abscesses did not decrease the need for further intervention and may not be necessary during an I&D procedure.'''

==Study Design==
Prospective, randomized, non blinded, single center trial comparing irrigation with no irrigation. The study was conducted in an academic ED with an annual census of ~110,00 patients.
 
==Population==
===Patient and Abscess Baseline Characteristics===
Median age was slightly lower in the Irrigation Group.  Irrigation group had a slightly higher rate of overlying cellulitis.
{| {{table}}
| align="center" style="background:#f0f0f0;"|'''Patient Characteristics'''
| align="center" style="background:#f0f0f0;"|'''Irrigation (95)'''
| align="center" style="background:#f0f0f0;"|'''No Irrigation (92)'''
|-
| Median Age||'''35'''||'''40'''
|-
| Cellulitis||'''61%'''||'''51%'''
|-
| Diabetes||17%||16%
|-
| Fever||3%||2%
|-
| Immunocompromised ||3%||2%
|}

There was no major difference in the size of the abscesses.
{| {{table}}
| align="center" style="background:#f0f0f0;"|'''Abscess Size'''
| align="center" style="background:#f0f0f0;"|'''Irrigation'''
| align="center" style="background:#f0f0f0;"|'''No Irrigation'''
|-
| Median||4.6 cm Irrigation||4.3 cm No Irrigation
|-
| Range||3-10 cm Irrigation ||1-11 cm No Irrigation
|}

Abscess location did not differ amongst groups.
{| {{table}}
| align="center" style="background:#f0f0f0;"|'''Abscess Location'''
| align="center" style="background:#f0f0f0;"|'''Irrigation'''
| align="center" style="background:#f0f0f0;"|'''No Irrigation'''
|-
| Face, Scalp||5%||9%
|-
| Neck||3%||5%
|-
| Chest, Breast, Back, Abdomen, Inguinal||13%||22%
|-
| Buttocks||20%||16%
|-
| Perineum, Perianal, Labial, Scrotal||7%||4%
|-
| Leg, foot||19%||21%
|}

There was a significant increase in the percent of patients who had packing in the Irrigation Group, as well as post procedure ABX's.
{| {{table}}
| align="center" style="background:#f0f0f0;"|'''Post Procedure'''
| align="center" style="background:#f0f0f0;"|'''Irrigation'''
| align="center" style="background:#f0f0f0;"|'''No Irrigation'''
|-
| Abscess Packed||'''89%'''||'''75%'''
|-
| IV ABX in ED||3%||8%
|-
| PO ABX in ED||42%||43%
|-
| ABX Rx’d||'''91%'''||'''73%'''
|}

===Inclusion Criteria===
*Patients over the age of 18 with a cutaneous abscess

===Exclusion Criteria===
*Pregnancy
*In police custody or prison resident
*Patients admitted to the hospital
*Operating room I&D
*Inability to follow up in 48 hours, or to provide contact information for 30 day follow up

==Interventions==
The intervention was to '''perform irrigation or no irrigation''' during the I&D procedure in the ED. Out of the 209 patients randomized, 105 were assigned to the irrigation group and 104 to the no irrigation group.

For the irrigation group, the type of solution and amount used was at the providers discretion. The most commonly used irrigant was a 100 mL NSS in  a squeeze bottle with a small caliber tip that can fit in an [[abscess]] pocket.

==Outcomes==
 

===Primary Outcome===
''Need for further intervention during subsequent 30 days. Predefined as one of the following: repeat I&D, ABX change, hospital admission for [[abscess]] related condition''
*Irrigation Group: 14 pts (15%)
*No Irrigation Group: 12 pts (13%)
**The only patient who required subsequent admission for the [[abscess]] was from the no irrigation group

Difference of 2%; 95% CI -8 to 12%

===Secondary Outcomes===
''Visual analog pain score post procedure''
*Irrigation Group: 5.6
*No Irrigation Group: 5.7

Difference 0.1; 95% CI -0.7 to 0.9

==Criticisms & Further Discussion==
*Lack of standardization of irrigation technique for the Irrigation Group
*Lack of standardization of packing and ABX usage, which lead to differences in these treatments in the two groups (irrigation group having increased rates of both)
*Relatively high use of ABX overall (82% of patients); may partly be explained by overall high incidence of overlying cellulitis in patients of both groups 
*Performed in a single institution 
*Further studies should evaluate a population with a lower incidence of cellulitis, and thus less incidence of ABX usage. 
*The use of ABX, as well as packing, is also of controversial benefit

==See Also==
*[[Incision and Drainage]]

==Funding==
No funding was reported for this study.



[[Category:EBQ]] [[Category:Dermatology]] [[Category:ID]] [[Category:Procedures]]