Ver el código de «Donepezil»

==Administration==
*Type: [[Acetylcholinesterase inhibitor]]
*Dosage Forms: Tab: 5 mg, 10 mg, 23 mg; ODT: 5 mg, 10 mg
*Routes of Administration: Oral
*Common Trade Names: Aricept

==Adult Dosing==
===[[Alzheimer dementia]], mild-moderate===
*5 mg PO qhs x4-6wk
**Increase to 10 mg PO qhs
===[[Alzheimer dementia]], moderate-severe===
*5 mg PO qhs x4-6wk
**Increase to 10mg PO qhs x3mo, then increase to 23mg PO qhs

==Pediatric Dosing==
Safety/efficacy not established in pediatric patients

==Special Populations==
*[[Drug pregnancy categories|Pregnancy Rating]]: C
*Lactation risk: N/A
===Renal Dosing===
*Adult: Not defined
*Pediatric: Not defined
===Hepatic Dosing===
*Adult: Not defined
*Pediatric: Not defined

==Contraindications==
*Allergy to class/drug

==Adverse Reactions==
===Serious===
*[[AV block]], [[Bradycardia]]
*[[Syncope]]
*[[Seizures]]
*GI Bleeding
*[[Hemolytic anemia]]
*Urinary obstruction
*[[Stevens-Johnson syndrome]], [[Toxic epidermal necrolysis]]

===Common===
*[[Nausea]], [[Vomiting]]
*[[Diarrhea]]
*[[Headache]], [[Dizziness]]
*Insomnia, abnormal dreams, [[fatigue]]
*Muscle Cramps
*Anorexia, weight loss
*Ecchymosis
*[[Depression]]
*[[Syncope]]
*[[Arthritis]]
*Urinary frequency

==Pharmacology==
*Half-life: 70h
*Metabolism: Liver; CYP450: 2D6, 3A4
*Excretion: Urine, Feces

==Mechanism of Action==
*Reversibly binds to and inactivates acetylcholinesterase

==Comments==


==See Also==


==References==
<references/>

[[Category:Pharmacology]]
[[Category:Neurology]]