Ver el código de «Dapsone»

==Administration==
*Type: [[Antibiotic]]
*Dosage Forms: 25,100
*Routes of Administration: Oral

==Adult Dosing==
===[[Hansen's disease]] ([[leprosy]])===
*paucibacillary: 100mg PO QD x6mo
**Use with rifampin
*multibacillary: 100mg PO QD x12mo
**Use with rifampin, clofazimine

===[[Bullous pemphigoid]]===
*50mg PO QD
**Use with topical or systemic [[corticosteroids]]

===Dermatitis herpetiformis===
*50mg PO QD

===[[Pneumocystis jirovecii pneumonia|PCP]]===
*Prophylaxis: 100mg/day PO divided QD-bid
**Off label use
*Treatment: 100mg PO QD x21 days
**Not 1st-line agent; use with [[trimethoprim]]
**Off label use

===[[Malaria]] suppression===
*100mg PO qwk
**Use with [[pyrimethamine]]
**Off label use

===[[Toxoplasmosis]] prophylaxis===
*50mg PO QD
**Off label use

==Pediatric Dosing==

==Special Populations==
*[[Drug Ratings in Pregnancy|Pregnancy Rating]]: C
*[[Lactation risk categories|Lactation risk]]: Probably unsafe
===Renal Dosing===
*No adjustment
===Hepatic Dosing===
*Caution advised with hepatic impairment
*CBC qwk x4, qmo x6, then q6mo thereafter
*LFTs at baseline, then periodically

==Contraindications==
*Allergy to class/drug
*caution if renal or hepatic impairment
*caution if impaired cardiovascular function

==Adverse Reactions==
===Serious===
*[[anemia]], hemolytic
*[[aplastic anemia]]
*agranulocytosis
*exfoliative dermatitis
*[[erythema multiforme]]
*[[toxic epidermal necrolysis]]

===Common===
*[[fever]]
*myalgia
*[[headache]]
*rigors
*fatigue
*malaise
*[[dizziness]]

==Pharmacology==
*Half-life: 28 hrs
*Metabolism: Liver, CYP450
*Excretion: Urine

==Mechanism of Action==

==Comments==

==See Also==

==References==
[[Category:Pharmacology]] [[Category:ID]]