Ver el código de «Cyproheptadine»

==Uses==
*Treatment of serotonin syndrome<ref>Graudins A, et al. Treatment of the serotonin syndrome with cyproheptadine. J Emerg Med. 1998;16(4):615-619. PMID 9696181</ref>

==Administration==
*Dosage Forms: 4mg tab, 2mg/5ml solution
*Routes of Administration: oral
*Common Trade Names: Periactin or Peritol

==Adult Dosing==
*initial dose of 12mg is recommended, followed by 2mg every two hours until clinical response is seen
==Pediatric Dosing==
*Children younger than two years can be given approximately 0.06mg/kg per dose every six hours, if needed (not to exceed 0.25mg/kg/day).
*Children two to six years can be given 2mg every six hours, if needed (not to exceed 12mg/day).
*Children 7 to 14 years can be given 4mg every six hours, if needed (not to exceed 16mg/day).

==Special Populations==
*[[Drug Ratings in Pregnancy|Pregnancy Rating]]: B

===Renal Dosing===
*No recommendations

===Hepatic Dosing===
*No recommendations

==Contraindications==
*Allergy to class/drug
*Treatment in newborns or nursing mothers

==Adverse Reactions==
===Serious===
*Hypotension
===Common===
*Sedation

==Pharmacology==
* Half-life: 1-4 hours
* Metabolism: Liver
* Excretion: Urine

==Mechanism of Action==
*Histamine-1 receptor antagonist
*5-HT1A and 5-HT2A (seritonin) antagonistic properties
*Weak anticholinergic activity

==Comments==


==Indications by Condition==
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==See Also==

==References==
*1. Boyer EW. Serotonin syndrome. In: UpToDate, Post TW (Ed), UpToDate, Waltham, MA. (Accessed on January 11, 2016.)

[[Category:Pharmacology]] [[Category:Toxicology]]