Ver el código de «Cocaine»

''This page is for the drug cocaine; for clinical effects see [[cocaine toxicity]]''
==Administration==
*Type: Local anesthetic
*Dosage Forms: 4% solution; 10% solution
*Routes of Administration: Topical
*Common Trade Names: Cocaine

==Adult Dosing==
*1-3 mg/kg, max dose of 200 mg
**Some literature suggests maximum dose of 100 mg
**Ideally use lowest effective dose

==Pediatric Dosing==
*1 mg/kg
**No clear safe dose established

==Special Populations==
*[[Drug pregnancy categories|Pregnancy Rating]]: Category C
*Lactation risk: Infant risk has been demonstrated
===Renal Dosing===
*Adult: N/A
*Pediatric: N/A
===Hepatic Dosing===
*Adult: N/A
*Pediatric: N/A

==Contraindications==
*Allergy to class/drug

==Adverse Reactions==
*[[Cocaine-associated chest pain]]
*Sympathomimetic qualities
**Tachycardia
**Fever
**Agitation
**Diaphoresis

==Pharmacology==
*Half-life: 50 to 75 minutes (5.5 hours benzoylecgonine metabolite)
*Metabolism: Plasma cholinesterase; liver
*Excretion: Renal

==Mechanism of Action==
*Blocks reuptake of serotonin, dopamine and norepinephrine
*Anesthetic effects achieved through sodium channel blockade

==Comments==


==See Also==
*[[Cocaine toxicity]]

==References==
Micromedex
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[[Category:Pharmacology]]