Ver el código de «Calcium chloride»

''See [[critical care quick reference]] for drug doses by weight.''
==General==
*Type: Mineral, [[Antidote]]
*Dosage Forms: injectable solution
*Dosage Strengths: 100 mg/mL
*Routes of Administration: IV
*Common Trade Names: 

==Adult Dosing==
*[[Hypocalcemia]] (emergent): 500-1000 mg IV over 5-10 minutes, repeat as needed
*Arrhythmias (emergent): 500-1000 mg IV over 5-10 minutes, repeat as needed
*[[Hypermagnesemia]]: 500-1000 mg IV over 2-5 minutes, repeat if CNS depression persists
*[[Calcium channel blocker toxicity]]: 1-2 g IV infused over 10-20 min; repeat every 20 minutes PRN up to 5 doses
*[[Beta-blocker toxicity]] (Refractory to glucagon/vasopressors): 1g IV bolus
*[[Hyperkalemia]]: 1g IV
*[[Cardiac Arrest]]: 1g IV (not recommended for routine use<ref>Neumar RW, Otto CW, Link MS, et al. Part 8: adult advanced cardiovascular life support: 2010 American Heart Association Guidelines for cardiopulmonary resuscitation and emergency cardiovascular care. Circulation. 2010;122(18 Suppl 3):729-767. doi: 10.1161/CIRCULATIONAHA.110.970988. [PubMed 20956224]</ref>)

==Pediatric Dosing==
''See [[critical care quick reference]] for drug doses by weight.''

==Special Populations==
*[[Drug Ratings in Pregnancy|Pregnancy Rating]]: C
*Lactation: Infant risk cannot be ruled out
*Renal Dosing: base dosing on serum Ca if CrCl <25, may need reduced dose if on HD
*Hepatic dosing: No adjustment

==Contraindications==
*Allergy to class/drug
*Current use of ceftriaxone sodium injection in neonates
*Ventricular fibrillation
*Do NOT administer for IM or subq
*Administer through central venous access except in cases of cardiac arrest
**High risk of extravasation and tissue necrosis

==Adverse Reactions==
===Serious===
*Vasodilation
*Tissue necrosis (if extravasated)
===Common===
*Burning sensation

==Pharmacology==
*Half-life: 
*Metabolism: 
*Excretion: Renal, fecal

==Mechanism of Action==
*Cofoactor in many enzymatic reactions, essential for neurotransmission, muscle contraction, and many signal transduction pathways

==See Also==
*[[Hypocalcemia]]
*[[Antidotes]]

==References==
<references/>

[[Category:Pharmacology]] [[Category:FEN]]