Ver el código de «Acrodermatitis enteropathica»

==Background==
*Disorder of zinc metabolism (either congenital mutation, abnormal zinc characteristics in mother's breast milk, or due to surgery affecting upper GI tract) that leads to effective zinc deficiency

==Clinical Features==
*[[Diarrhea]], steatorrhea
*Irritation/inflammation of skin around body openings (e.g. mouth, anus, eyes, hands/feet)
**Typically [[vesiculobullous rashes|vesiculobullous]] initially, then dry and resemble [[psoriasis]] rash
*Nails may become abnormal
*[[Alopecia]]
*[[Conjunctivitis]]

==Differential Diagnosis==
{{Vitamin deficiencies DDX}}

==Evaluation==
*Serum zinc level typically low
*Reduced serum alkaline phosphatase levels often supportive evidence for zinc deficiency, as zinc is a cofactor for alkaline phosphatase activity<ref>Kiliç I, Ozalp I, Coŝkun T, Tokatli A, Emre S, Saldamli I, Köksel H, Ozboy O. The effect of zinc-supplemented bread consumption on school children with asymptomatic zinc deficiency. J Pediatr Gastroenterol Nutr. 1998 Feb;26(2):167-71. doi: 10.1097/00005176-199802000-00008. PMID: 9481631.</ref>

==Management==
*Zinc sulfate supplementation (13.2 mg/kg/day, totaling ~3mg/kg/day of elemental zinc)
*Monitor zinc levels every 4-6 months

==Disposition==


==See Also==


==External Links==
*https://rarediseases.org/rare-diseases/acrodermatitis-enteropathica/

==References==
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[[Category:FEN]]