Ver el código de «Acanthosis nigricans»

==Background==
{{Skin anatomy background images}}
*Multiple forms, but malignant acanthosis nigricans is most important
**Most commonly associated with [[colon cancer|colonic adenocarcinoma]], gastric cancer, ovarian cancer
**Also associated with other dermal manifestations of internal cancers
*Associated with GI and GU malignancies, which may have concomitant weight loss
*Non malignant form may be associated with endocrine abnormalities, such as insulin resistance

==Clinical Features==
[[File:malignant_acanthosis_nigricans_ovarian.png|thumb|Malignant acanthosis nigricans secondary to ovarian cancer]]
*Hyperpigmented, velvety
*Plaques
*Most commonly intertriginous areas, posterior neck
*May have concurrent acrochordons, skin tags

==Differential Diagnosis==
{{DDX dark raised lesions}}

==Evaluation==
===Workup===

===Diagnosis===
*Red flags for ''malignant'' acanthosis nigricans:
**Oral involvement (up to 50%)
**Rapid appearance of lesions
**Extensive involvement
**Older adult
**Unexplained weight loss 
**Lesions in atypical sites such as palms/soles, mucous membranes

==Management==

==Disposition==

==External Links==

==See Also==
*[[Seborrheic keratosis]]
*[[Dark raised skin lesions]]

==References==
<references/>

*Schwarzenberger K, Callen JP. Chapter 53: Dermatologic manifestations in patients with systemic disease. In: Bolognia JL,‎ Schaffer JV,‎ Cerroni L, eds. Dermatology. 4th ed. Philadelphia, PA: Elsevier; 2017:820.

[[Category:Dermatology]]