Ver el código de «Trospium»

==Administration==
*Type: Anticholinergic
*Dosage Forms: 20mg
*Routes of Administration: Oral
*Common Trade Names: Trospium Chloride 

==Adult Dosing==
*Overactive bladder: 20mg twice daily
==Pediatric Dosing==
*Not defined
==Geriatric Dosing==
*Elderly ≥75 years: consider initial design 20mg one daily (based on tolerability)

==Special Populations==
*[[Drug Ratings in Pregnancy|Pregnancy Rating]]: C
*[[Lactation risk categories|Lactation risk]]: Not defined
===Renal Dosing===
*Adult: 
**CrCl ≥30ml/minute: no dose adjustment required
**CrCl <30ml/minute: 20mg once daily at bedtime 
*Pediatric: Not defined
===Hepatic Dosing===
*Adult: Not defined
*Pediatric: Not defined

==Contraindications==
*Allergy to class/drug
*Urinary retention
*Gastric retention
*Narrowed-angle glaucoma


==Adverse Reactions==
===Serious===
*Tachycardia/SVT (<2%)
*Hypertensive crisis (<1%)
*Rhabdomyolysis (<1%)
*Steven-Johnson Syndrome (<1%)
===Common===
*Xerostomia
*Headache
*Constipation
*Urinary tract infection
==Pharmacology==
*Half-life: 20 h
*Metabolism: via hydrolysis and conjugation, forms metabolites
*Excretion: feces (85%), urine (6%)

==Mechanism of Action==
Antagonize effect of acetylcholine on muscarinic receptors, reduce smooth muscle tone of the bladder
==Comments==

==See Also==

==References==
<references/>
[[Category:Pharmacology]]