Ver el código de «Multidose activated charcoal»

==Background==
*Method of enhanced elimination that uses multiple doses of activated charcoal
*No evidence to suggest that MDAC decreases morbidity or mortality
**Some evidence shows that MDAC increases the elimination of certain drugs (further explained below)

==Dosing==
*12.5 g/hr in divided doses (eg. 50g Q4hr)

==Contraindications==
* Same as with [[Single Dose Activated Charcoal (SDAC)]]
*'''Intestinal obstruction''' (absolute)
*Decreased gut motility (relative)

==Indications==
*Mnemonic: '''''T'''''hese '''''P'''''eople '''''D'''''rink '''''C'''''harcoal '''''Q'''''uickly
**Theophylline
**Phenobarbital
**Dapsone
**Carbamazepine
**Quinine

==Mechanism of Action==
#Stops enterohepatic circulation 
#Increases passive diffusion and acts as a sink for the xenobiotics
#Binds drugs in extended release formulations

==See Also==
[[Activated Charcoal]]

==References==
<references/>
*http://www.clintox.org/documents/positionpapers/MultipleDoseActivatedCharcoal.pdf
*Uptodate

[[Category:Toxicology]]