Ver el código de «Methylprednisolone»

==General==
*Type: [[Corticosteroid]]
*Dosage Forms: IM; IV
*Common Trade Names: Medrol, Solu-Medrol

==Adult Dosing==
===[[Anaphylaxis]]===
*125 mg IV 

==Pediatric Dosing==
===[[Anaphylaxis]]===
*2mg/kg

==Special Populations==
*[[Drug Ratings in Pregnancy|Pregnancy Rating]]: C(US)
*Lactation: Oral maternal doses to 8mg daily is safe. Recommend waiting 2-8 hours after infusion of 1 gm. <ref>[http://toxnet.nlm.nih.gov/cgi-bin/sis/search2/f?./temp/~w439Lx:1 Lactmed: Methylprednisolone] </ref>
*Renal Dosing
**Adult: not available
**Pediatric: not available
*Hepatic Dosing
**Adult: not available
**Pediatric: not available

===[[EBQ:High Dose Steroids in Cord Injury#Major Points|Controversial Use in Spinal Cord Injury]]===
*Steroid use for spinal cord injury was a controversial treatment during the 1990s and 2000s, with the NASCIS II and III studies reporting positive outcomes in a subgroup analysis of patients who received methylpredisolone within 8 hours of injury. Multiple cochrane reviews performed by the author of the NASCIS trials concluded neurological improvement after injury, but a review of all individual studies demonstrate negative outcomes for both the retrospective and the prospective trials<ref>Steroids for Spinal Cord Injury http://www.trauma.org/archive/spine/steroids.html#NASCIS_1.2C_USA_1984</ref>. Most recent guidelines from the Congress of Neurological Surgeons and American Association of Neurological Surgeons discourage against the use of steroids in spinal cord injury, citing harmful side effects including death.<ref>Anderson P. New CNS/AANS Guidelines Discourage Steroids in Spinal Injury. Medscape Medical News. Mar 28 2013</ref>

==Contraindications==
*Allergy to class/drug

==Adverse Reactions==
===Serious===

===Common===

==Pharmacology==
*Half-life: 
*Metabolism: 
*Excretion: 
*Mechanism of Action:

==See Also==

==References==
<references/>
[[Category:Pharmacology]]