Ver el código de «Tramadol»

==General==
*Type: opioid
*Dosage Forms: PO
*Common Trade Names: Ultram, Ryzolt

==Adult Dosing==
===General===
Pain:
*50-100 mg PO q4-6h PRN, 

 Chronic severe pain: 
*100-300 mg ER PO QDAY

==Pediatric Dosing==
Not Currently recommended

==Special Populations==
*[[Drug Ratings in Pregnancy|Pregnancy Rating]]: C
*[[Lactation Risk Categories]]: Probably safe
*Renal Dosing
**Adult: CrCL < 30: given q12h, max 200 mg/day
**Pediatric: none
*Hepatic Dosing
**Adult: cirrhosis: 50 mg q12h, max 100 mg/day
**Pediatric: not defined

==Contraindications==
*Allergy to class/drug
*asthma, acute
* respiratory depression
* severe hepatic impairment
* severe renal impairment
* acute alcohol intoxication

==Adverse Reactions==
===Serious===
*Respiratory Depression
* suicidal ideation
*Seizures
*anaphylaxis
*serotonin syndrome
* steven johnson syndrome

===Common===
*Nausea
*Rash
*Headache
*Fatigue
*xerostomia
*constipation
*Tremor
* insomnia

==Pharmacology==
*Half-life: 6.3 - 7.9 hour
*Metabolism: Liver
*Excretion: urine
*Mechanism of Action:exact mechanism unknown, binds to mu opioid receptors and weakly inhibits NE/Serotonin reuptake

[[Category:Drugs]]