Ver el código de «Acute generalized exanthematous pustulosis»

==Background==
*T-cell mediated [[rash]] with systemic features
*>90% of cases attributable to a medication (usually an antibiotic)
*Mortality rate of ~5%

==Clinical Features==
[[File:Acute generalized exanthematous pustulosis.png|thumb|Acute generalized exanthematous pustulosis]]
*Onset 1-5 days after starting causative medication
*[[Rash]]:
**Large areas of edematous erythema with numerous small, non-follicular pustules
**Predominantly affects main body folds and upper trunk, but can involve face
**NO mucous membrane involvement (in contrast to SJS/TEN)
*Systemic findings:
**[[Fever]]
**[[Leukocytosis]], specifically neutrophilia
**+/- Facial swelling
**+/- [[Hepatitis]]
**+/- [[Eosinophilia]]

==Differential Diagnosis==
*[[Erythema Multiforme]]
*[[Stevens-Johnson syndrome and toxic epidermal necrolysis]]
*[[Staphylococcal scalded skin syndrome]]
*[[Erythroderma]]
*[[Toxic Shock Syndrome]]
*[[Drug rash]]
*[[DRESS syndrome]]

{{Erythematous rash DDX}}

==Evaluation==
*Clinical diagnosis
*CBC
*BMP
*LFTs

==Management==
*Stop inciting agent
*IVF- treat similar to fluid resuscitation in [[burns]]
*Wound care, infection control
 
==Disposition==
*Admit

==See Also==
*[[Erythematous rash]]
*[[Stevens-Johnson syndrome and toxic epidermal necrolysis]]
*[[DRESS syndrome]]

==External Links==

==References==
<references/>

[[Category:Dermatology]]