Ver el código de «Clonazepam»

==Administration==
*Type: [[Benzodiazepine]]
*Dosage Forms:
*Routes of Administration: PO (tablet or ODT)
*Common Trade Names: Klonopin

==Adult Dosing==
*0.25-6mg PO q8-24h

==Pediatric Dosing==
*6-10yo or <30kg: 0.01-0.2 mg/kg/day PO divided q8h
*>10yo: 1.5-20mg/day PO divided q8h

==Special Populations==
===[[Drug pregnancy categories|Pregnancy Rating]]===
*D

===Lactation risk===
*Excreted in breastmilk- avoid use or monitor infant closely for sedation

===Renal Dosing===
*No adjustment

===Hepatic Dosing===
*Do not use in significant hepatic impairment

 ==Contraindications==
*Allergy to class/drug
*Significant hepatic impairment
*Acute narrow angle glaucoma
*Caution with:
**Compromised respiratory function (e.g. COPD, sleep apnea, myasthenia gravis)
**Concomitant CNS depressants
**History of ETOH/substance abuse
**Depression, psychosis, suicidal ideation
**Porphyria
**Elderly

==Adverse Reactions==
===Serious===
*Respiratory depression
*CNS depression, coma 
*Paradoxical agitation, anxiety, psychosis
*Suicidal ideation
*Abuse/dependence
*Withdrawal seizures

===Common===
*Somnolence/fatigue
*Confusion, memory impairment, abnormal coordination, dysarthria, dizziness
*Depression
*Impotence, decreased libido
*URI, cough
*Urinary frequency

==Pharmacology==
*Half-life: 17-60h (adults); 22-33h (children)
*Metabolism: Hepatic
*Excretion: Urinary

==Mechanism of Action==
*Long-acting [[benzodiazepine]]

==Comments==


==See Also==
*[[Benzodiazepine toxicity]]
*[[Benzodiazepine withdrawal]]

==References==
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[[Category:Pharmacology]]