Ver el código de «Dobutamine»

==General==
*Type: [[Vasopressors]]
*Dosage Forms:
*Common Trade Names:

==Adult Dosing==
===Dosing===
*2-20mcg/kg/min
**10mcg works for most
*May use in peripheral IV
===Rate of Titration===
*Q2-5 min

==Pediatric Dosing==

==Special Populations==
*[[Drug Ratings in Pregnancy|Pregnancy Rating]]:
*Lactation:
** Unknown if Dobutamine passes into breast milk 
*Renal Dosing
**Adult
*** Not defined
**Pediatric
*** Not defined
*Hepatic Dosing
**Adult
*** Not defined
**Pediatric
*** Not defined

==Contraindications==
*Allergy to class/drug

==Adverse Reactions==
*Tachyarrhythmias
*Myocardial ischemia 
*[[Hypotension]] as β<sub>2</sub> effect may result in vasodilation
**Caution if SBP <90

===Serious===

===Common===

==Pharmacology==
*Half-life: 
*Metabolism: 
*Excretion: 
*Mechanism of Action:β<sub>1</sub> stimulation with variable BP effects
===Primary Receptor===
*β<sub>1</sub> 
*β<sub>2</sub>
===Relative Effects===
*↑↑↑SV
*↑↑HR → increases oxygen demand of heart → can worsen ischemia 
*↓SVR (transient, from β<sub>2</sub> agonism) 

==Notes==
===Indications===
*Cardiogenic shock
**initial agent in low-output heart failure without requiring BP support
*Tricyclic overdose
*septic shock with low cardiac output to improve blood flow 

==See Also==
http://www.atsjournals.org/doi/abs/10.1164/rccm.201006-0972CI?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed#readcube-epdf

==References==
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[[Category:Pharmacology]]