Ver el código de «Phenylephrine»

==General==
*Type: [[Vasopressors]]
*Dosage Forms:
*Common Trade Names: 

==Adult Dosing==
===General===
*Start 100-200mcg/min then taper down
**40-60mcg/min works for most

===Low Flow [[Priapism]]===
*Inject base of penis with 29-Ga needle (after blood aspiration to confirm position) 0.5-1mL q3-5min until resolution or one hour (max 1500mcg) 
*Typical doses are 100-500 mcg every 3-5min, max 1 mg over 1 hour
**Dilute phenylephrine 1mg in 9mL NS for final concentration of 100mcg/mL 
**For 500 mcg/ml, take 0.5 ml of 10mg/ml phenylephrine, and dilute in 9.5 cc NS

==Pediatric Dosing==

==Special Populations==
*[[Drug Ratings in Pregnancy|Pregnancy Rating]]: C
*Lactation: infant risk cannot be ruled out
*Renal Dosing
**Adult
**Pediatric
*Hepatic Dosing
**Adult
**Pediatric

==Contraindications==
*Allergy to class/drug

==Adverse Reactions==
*Baroreceptor-mediated reflex bradycardia
*If extravasates use phentolamine

===Serious===

===Common===

==Pharmacology==
*Half-life: 
*Metabolism: 
*Excretion: 
*Mechanism of Action:
===Primary Receptor===
*α1
===Relative Effects===
*↑SVR
*↓HR (reflex bradycardia) 

==Notes==
*Use with caution in patients with spinal cord injury-related bradycardia 
*Useful for treatment of vasodilatory shock when norepinephrine or [[dopamine]] have precipitated tachyarrhythmias
*In patients with ↓LV function, unopposed α1 may lead to decreased CO or myocardial ischemia
**However clinical trials do not support these effects when used in clinically appropriate dose range

===Indication===
*Neurogenic Shock

==See Also==

==References==

<references/>
[[Category:Pharmacology]]